AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study

[1] Zhou G(2001)Role of AMP-activated protein kinase in mechanism of metformin action J Clin Invest 108 1167-1174

[2] Myers R(2005)The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin Science 310 1642-1646

[3] Li Y(1998)Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) Lancet 352 854-865

[4] Shaw RJ(2008)AMPK: a key regulator of energy balance in the single cell and the whole organism Int J Obes 32 S7-S12

[5] Lamia KA(2009)AMPK: an emerging drug target for diabetes and the metabolic syndrome Cell Metab 9 407-416

[6] Vasquez D(1994)Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase FEBS Lett 353 33-36

[7] Hardie DG(1990)Identification and role of the basal phosphorylation site on hormone-sensitive lipase Eur J Biochem 191 245-250

[8] Zhang BB(1995)5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur J Biochem 229 558-565

[9] Zhou G(2005)Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes J Biol Chem 280 25250-25257

[10] Li C(2007)Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes Biochem J 403 473-481

[1] Zhou G(2001)Role of AMP-activated protein kinase in mechanism of metformin action J Clin Invest 108 1167-1174

[2] Myers R(2005)The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin Science 310 1642-1646

[3] Li Y(1998)Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) Lancet 352 854-865

[4] Shaw RJ(2008)AMPK: a key regulator of energy balance in the single cell and the whole organism Int J Obes 32 S7-S12

[5] Lamia KA(2009)AMPK: an emerging drug target for diabetes and the metabolic syndrome Cell Metab 9 407-416

[6] Vasquez D(1994)Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase FEBS Lett 353 33-36

[7] Hardie DG(1990)Identification and role of the basal phosphorylation site on hormone-sensitive lipase Eur J Biochem 191 245-250

[8] Zhang BB(1995)5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur J Biochem 229 558-565

[9] Zhou G(2005)Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes J Biol Chem 280 25250-25257

[10] Li C(2007)Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes Biochem J 403 473-481