Mechanisms of Disease: mutations of G proteins and G-protein-coupled receptors in endocrine diseases

被引：0

作者：

Andrea G Lania

Giovanna Mantovani

Anna Spada

机构：

[1] Endocrine Unit,a Research Associate, G Mantovani is a Postdoctoral Fellow and A Spada is a Professor of Endocrinology at the Department of Medical Sciences

[2] University of Milan,undefined

[3] Fondazione IRCCS Ospedale Maggiore,undefined

[4] Policlinico,undefined

[5] Mangiagalli,undefined

来源：

Nature Clinical Practice Endocrinology & Metabolism | 2006年 / 2卷

关键词：

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学科分类号：

摘要：

Many hormones use G-protein-coupled receptors and G proteins in the target cell to transduce their signals. A range of disease-causing mutations have been characterized that mimic states of hormone deficiency or excess. This Review describes these mutations, and their resultant clinical and biochemical features.

引用

页码：681 / 693

页数：12

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