A phase II trial of cyclophosphamide, epirubicin and vinorelbine in the treatment of advanced breast cancer

被引：0
作者：
E. Esteban
González de Sande
J. Puertas
J. Fra
I. Palacio
J.M. Vieitez
J.L. Fernández
I. Muñiz
A. Modollel
J. Carrasco
M. Sala
A.J. Lacave
机构：
来源：
Breast Cancer Research and Treatment | 2000年 / 62卷
关键词：
advanced breast cancer; vinorelbine; epirubicin; cyclophosphamide; combination chemotherapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background.Vinorelbine (Navelbin®; N) has proven to be active in patients with advanced breast cancer (ABC) and cyclophosphamide (C) and epirubicin (Epiadriamycin®: E) are still among the main cytostatic agents against this tumor. On this basis was carried out a study to determine the activity and toxicity of the combination of these three agents (CEN).
引用
收藏
页码：127 / 133
页数：6
相关论文
共 50 条
[21]   Sequential docetaxel followed by epirubicin-vinorelbine as first-line chemotherapy in advanced breast cancer [J].
Vici, P ;
Foggi, P ;
Colucci, G ;
Capomolla, E ;
Brandi, M ;
Giotta, F ;
Gebbia, N ;
Di Lauro, L ;
Valerio, MR ;
Paoletti, G ;
Belli, F ;
Pizza, C ;
Giannarelli, D ;
Lopez, M .
ANTICANCER RESEARCH, 2005, 25 (2B) :1309-1314
[22]   A Phase II Study of Epirubicin and Cyclophosphamide Followed by Weekly Paclitaxel with or without Trastuzumab as Primary Systemic Therapy in Locally Advanced Breast Cancer [J].
Shimizu, Tadao ;
Hirano, Akira ;
Kamimura, Mari ;
Ogura, Kaoru ;
Kim, Naomi ;
Watanabe, Osamu ;
Kinoshita, Jun ;
Kimura, Kiyomi ;
Ogawa, Kenji ;
Fujibayashi, Mariko .
ANTICANCER RESEARCH, 2010, 30 (11) :4665-4671
[23]   Doxorubicin plus Ifosfamide as Salvage Treatment for Patients with Advanced Breast Cancer Refractory to Epirubicin plus Cyclophosphamide [J].
Aristidis Polyzos ;
C. Kosmas ;
N. Tsavaris ;
C. Markopoulos ;
N. Kalahanis ;
O. Papadopoulos ;
T. Arnaouti ;
P. P. Sfikakis .
Clinical Drug Investigation, 2000, 19 :349-355
[24]   A phase II trial of high dose epirubicin in patients with advanced breast carcinoma [J].
Miller, KD ;
Munshi, N ;
Loesch, D ;
Einhorn, LH ;
Sledge, GW .
CANCER, 2000, 88 (02) :375-380
[25]   Phase III trial of liposomal doxorubicin and cyclophosphamide compared with epirubicin and cyclophosphamide as first-line therapy for metastatic breast cancer [J].
Chan, S ;
Davidson, N ;
Juozaityte, E ;
Erdkamp, F ;
Pluzanska, A ;
Azarnia, N ;
Lee, LW .
ANNALS OF ONCOLOGY, 2004, 15 (10) :1527-1534
[26]   PHASE-II STUDY OF HIGH-DOSE EPIRUBICIN IN COMBINATION WITH CYCLOPHOSPHAMIDE IN PATIENTS WITH ADVANCED BREAST-CANCER [J].
LEVI, JA ;
BEITH, JM ;
SNYDER, RD ;
TATTERSALL, MH ;
BELL, D ;
WHEELER, H .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1995, 25 (05) :474-478
[27]   Phase I/II Trial of Vinorelbine and Sorafenib in Metastatic Breast Cancer [J].
Luu, Thehang ;
Frankel, Paul ;
Chung, Cathie ;
Chow, Warren ;
Mortimer, Joanne ;
Hurria, Arti ;
Somlo, George .
CLINICAL BREAST CANCER, 2014, 14 (02) :94-100
[28]   Neoadjuvant vinorelbine/epirubicin (VE) versus standard adriamycin/cyclophosphamide (AC) in operable breast cancer: analysis of response and tolerability in a randomised phase III trial (TOPIC 2) [J].
Chua, S ;
Smith, IE ;
A'Hern, RP ;
Coombes, GA ;
Hickish, TF ;
Robinson, AC ;
Laing, RW ;
O'Brien, MER ;
Ebbs, SR ;
Hong, A ;
Wardley, A ;
Mughal, T ;
Verrill, M ;
Dubois, D ;
Bliss, JM .
ANNALS OF ONCOLOGY, 2005, 16 (09) :1435-1441
[29]   Treatment of advanced, refractory breast cancer with alternating docetaxel and epirubicin/cyclophosphamide plus human granulocyte colony-stimulating factor [J].
Werner Kwasny ;
Gabriela Kornek ;
Karin Haider ;
Julia Valencak ;
Herbert Ulrich-Pur ;
Melitta Penz ;
Friedrich Lang ;
Dieter Depisch ;
Werner Scheithauer .
Breast Cancer Research and Treatment, 2000, 63 :235-241
[30]   Treatment of advanced, refractory breast cancer with alternating docetaxel and epirubicin/cyclophosphamide plus human granulocyte colony-stimulating factor [J].
Kwasny, W ;
Kornek, G ;
Haider, K ;
Valencak, J ;
Ulrich-Pur, H ;
Penz, M ;
Lang, F ;
Depisch, D ;
Scheithauer, W .
BREAST CANCER RESEARCH AND TREATMENT, 2000, 63 (03) :235-241
12345