Anaplastic carcinoma of the pancreas with rhabdoid features and hyaline globule-like structures

被引：0
作者：
Naoto Kuroda
Shin-ichi Iwamura
Nokiaki Fujishima
Masahiko Ohara
Takashi Hirouchi
Keiko Mizuno
Yoshihiro Hayashi
Gang-Hong Lee
机构：
[1] Kochi Red Cross Hospital,Departments of Pathology and Laboratory Medicine
[2] Kochi Red Cross Hospital,Department of Internal Medicine
[3] Kochi Red Cross Hospital,Department of Surgery
[4] Kochi Medical School,Department of Pathology, Program of Bioregulation and Genetics
[5] Kochi University,undefined
来源：
Medical Molecular Morphology | 2007年 / 40卷
关键词：
Anaplastic carcinoma; Pancreas; Hyaline globule-like structures; Ultrastructure;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A 59-year-old Japanese man presented with a giant submucosal tumor with ulceration during follow-up of duodenal ulcer. Pancreaticoduodenectomy was undertaken, and subsequent histological examination of the tumor disclosed anaplastic carcinoma of the pancreas head. The carcinoma components contained adenocarcinoma and squamous cell carcinoma. Additionally, undifferentiated spindle or pleomorphic cells were seen in continuity with the carcinoma component. Undifferentiated neoplastic cells with rhabdoid features and with hyaline globule-like structures positive for PAS stain with diastase pretreatment were also observed. Immunohistochemically, cytoplasmic inclusions corresponding to rhabdoid features showed aggregates of vimentin. Ultrastructurally, hyaline globule-like structures corresponded to lysosomes. Finally, we report here the first case of anaplastic carcinoma of the pancreas with hyaline globule-like structures.
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页码：168 / 171
页数：3
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