Platelet-Derived Endothelial Cell Growth Factor Mediates Rho-Associated Coiled-Coil Domain Kinase Messenger RNA Expression and Promotes Cell Motility

被引：0
作者：
Keiji Yoshinaga
Hiroshi Inoue
Fumiaki Tanaka
Koshi Mimori
Tohru Utsunomiya
Masaki Mori
机构：
[1] Medical Institute of Bioregulation,Department of Molecular and Surgical Oncology
[2] Kyushu University,Department of Molecular and Surgical Oncology
[3] Medical Institute of Bioregulation,undefined
[4] Kyushu University,undefined
来源：
Annals of Surgical Oncology | 2003年 / 10卷
关键词：
PD-ECGF; ROCK1; Cell motility; cDNA microarray;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Platelet-derived endothelial cell growth factor (PD-ECGF), whose expression is increased in several cancers, is an endothelial cell mitogen and has chemotactic activity in vitro and angiogenic activity in vivo. Tumors with high PD-ECGF expression tend to have frequent lymph node metastasis and are associated with poor outcome.
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页码：582 / 587
页数：5
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