Norovirus P particle-based tau vaccine-generated phosphorylated tau antibodies markedly ameliorate tau pathology and improve behavioral deficits in mouse model of Alzheimer’s disease

被引：0
|
作者：
Yao Sun
Yongqing Guo
Xuejian Feng
Lu Fu
Yayuan Zheng
Yue Dong
Yong Zhang
Xianghui Yu
Wei Kong
Hui Wu
机构：
[1] Jilin University,National Engineering Laboratory for AIDS Vaccine, School of Life Sciences
[2] Jilin Agricultural University,Laboratory of Pathogenic Microbiology and Immunology, College of Life Science
[3] Jilin University,Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences
来源：
Signal Transduction and Targeted Therapy | / 6卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Norovirus P particle-based tau vaccine-generated phosphorylated tau antibodies markedly ameliorate tau pathology and improve behavioral deficits in mouse model of Alzheimer's disease
    Sun, Yao
    Guo, Yongqing
    Feng, Xuejian
    Fu, Lu
    Zheng, Yayuan
    Dong, Yue
    Zhang, Yong
    Yu, Xianghui
    Kong, Wei
    Wu, Hui
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 6 (01)
  • [2] Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease
    Gibbons, Garrett S.
    Kim, Soo-Jung
    Wu, Qihui
    Riddle, Dawn M.
    Leight, Susan N.
    Changolkar, Lakshmi
    Xu, Hong
    Meymand, Emily S.
    O'Reilly, Mia
    Zhang, Bin
    Brunden, Kurt R.
    Trojanowski, John Q.
    Lee, Virginia M. Y.
    MOLECULAR NEURODEGENERATION, 2020, 15 (01)
  • [3] Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease
    Garrett S. Gibbons
    Soo-Jung Kim
    Qihui Wu
    Dawn M. Riddle
    Susan N. Leight
    Lakshmi Changolkar
    Hong Xu
    Emily S. Meymand
    Mia O’Reilly
    Bin Zhang
    Kurt R. Brunden
    John Q. Trojanowski
    Virginia M. Y. Lee
    Molecular Neurodegeneration, 15
  • [4] Fibrinogen-tau Aggregates Exacerbate Tau Pathology and Memory Deficits in Alzheimer's Disease Model Mice
    Wen, Tingting
    Meng, Lanxia
    Liu, Han
    Zhang, Qian
    Dai, Lijun
    Huang, Liqin
    Dan, Liang
    Zhu, Kedong
    Luo, Jiaying
    Zhang, Zhaohui
    NEUROSCIENCE BULLETIN, 2025,
  • [5] Induction and spreading of tau pathology in a mouse model of Alzheimer's disease
    Clavaguera, Florence
    Goedert, Michel
    ToInay, Markus
    M S-MEDECINE SCIENCES, 2010, 26 (02): : 121 - 124
  • [6] Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model
    Castillo-Carranza, Diana L.
    Guerrero-Munoz, Marcos J.
    Sengupta, Urmi
    Hernandez, Caterina
    Barrett, Alan D. T.
    Dineley, Kelly
    Kayed, Rakez
    JOURNAL OF NEUROSCIENCE, 2015, 35 (12): : 4857 - 4868
  • [7] Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease
    Ayalon, Gai
    Lee, Seung-Hye
    Adolfsson, Oskar
    Foo-Atkins, Corinne
    Atwal, Jasvinder K.
    Blendstrup, Mira
    Booler, Helen
    Bravo, Joseph
    Brendza, Robert
    Brunstein, Flavia
    Chan, Ruby
    Chandra, Priya
    Couch, Jessica A.
    Datwani, Akash
    Demeule, Barthelemy
    DiCara, Danielle
    Erickson, Rich
    Ernst, James A.
    Foreman, Oded
    He, Dongping
    Hotzel, Isidro
    Keeley, Michael
    Kwok, Michael C. M.
    Lafrance-Vanasse, Julien
    Lin, Han
    Lu, Yanmei
    Luk, Wilman
    Manser, Paul
    Muhs, Andreas
    Ngu, Hai
    Pfeifer, Andrea
    Pihlgren, Maria
    Rao, Gautham K.
    Scearce-Levie, Kimberly
    Schauer, Stephen P.
    Smith, William B.
    Solanoy, Hilda
    Teng, Edmond
    Wildsmith, Kristin R.
    Yadav, Daniela Bumbaca
    Ying, Yong
    Fuji, Reina N.
    Kerchner, Geoffrey A.
    SCIENCE TRANSLATIONAL MEDICINE, 2021, 13 (593)
  • [8] Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer's disease
    Sun, Xiao-ying
    Li, Ling-jie
    Dong, Quan-Xiu
    Zhu, Jie
    Huang, Ya-ru
    Hou, Sheng-jie
    Yu, Xiao-lin
    Liu, Rui-tian
    JOURNAL OF NEUROINFLAMMATION, 2021, 18 (01)
  • [9] Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease
    Xiao-ying Sun
    Ling-jie Li
    Quan-Xiu Dong
    Jie Zhu
    Ya-ru Huang
    Sheng-jie Hou
    Xiao-lin Yu
    Rui-tian Liu
    Journal of Neuroinflammation, 18
  • [10] Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model
    Parrella, Edoardo
    Maxim, Tom
    Maialetti, Francesca
    Zhang, Lu
    Wan, Junxiang
    Wei, Min
    Cohen, Pinchas
    Fontana, Luigi
    Longo, Valter D.
    AGING CELL, 2013, 12 (02) : 257 - 268
12345