Thailand orthohantavirus infection in patients with chronic kidney disease of unknown aetiology in Sri Lanka

被引：0
作者：
K. Yoshimatsu
C. D. Gamage
Y. D. Sarathkumara
T. Kulendiran
D. S. Muthusinghe
N. Nanayakkara
L. Gunarathne
K. Shimizu
Y. Tsuda
J. Arikawa
机构：
[1] Hokkaido University,Department of Microbiology and Immunology, Faculty of Medicine
[2] Hokkaido University,Graduate School of Infectious Disease
[3] University of Peradeniya,Department of Microbiology, Faculty of Medicine
[4] University of Peradeniya,Postgraduate Institute of Science
[5] Teaching Hospital Kandy,Nephrology and Transplantation Unit
[6] Renal Clinic,Graduate School of Medicine
[7] District Hospital,undefined
[8] Hokkaido University,undefined
来源：
Archives of Virology | 2019年 / 164卷
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摘要：
Chronic kidney disease of unknown aetiology (CKDu) reported in Sri Lanka and other countries is a mysterious and serious disease. Recently, we reported a high seroprevalence of antibodies to a hantavirus antigen among CKDu patients in Girandurukotte, Badulla district, Sri Lanka. However, the type of hantavirus with which the residents were infected was not determined. In this study, a total of 89 seropositive sera were examined to identify their serotypes using an indirect immunofluorescent antibody assay, a truncated-N-protein-based enzyme-linked immunosorbent assay, and a cross-neutralization test. These results indicated that the residents in this area were frequently infected with Thailand orthohantavirus or an antigenically related virus.
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页码：267 / 271
页数：4
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