Stability of Mefenamic Acid in the Inclusion Complex with β-Cyclodextrin in the Solid Phase

被引:0
|
作者
Teresa Hładoń
Jan Pawlaczyk
Barbara Szafran
机构
[1] Karol Marcinkowski University of Medical Sciences,Department of Inorganic and Analytical Chemistry
来源
Journal of inclusion phenomena and macrocyclic chemistry | 1999年 / 35卷
关键词
β-Cyclodextrin complex; mefenamic acid; X-ray and thermogravimetric analyses; complex stability constants; stability studies;
D O I
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学科分类号
摘要
The inclusion complex of mefenamic acid with β-cyclodextrin was obtained by the method of coprecipitation from diethyl ether. The product was identified by the thermogravimetric and X-ray methods. The complex stability constants were determined by the potentiometric method. The effect of β-CD on the solubility and stability of mefenamic acid was analysed.
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页码:497 / 506
页数:9
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