Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer’s disease

被引:0
作者
Ellis Patrick
Sathyapriya Rajagopal
Hon-Kit Andus Wong
Cristin McCabe
Jishu Xu
Anna Tang
Selina H. Imboywa
Julie A. Schneider
Nathalie Pochet
Anna M. Krichevsky
Lori B. Chibnik
David A. Bennett
Philip L. De Jager
机构
[1] Program in Translational NeuroPsychiatric Genomics,Departments of Neurology and Psychiatry, Brigham and Women’s Hospital
[2] Institute for the Neurosciences,undefined
[3] Harvard Medical School,undefined
[4] Program in Medical and Population Genetics,undefined
[5] Broad Institute,undefined
[6] Rush Alzheimer’s Disease Center,undefined
[7] Rush University Medical Center,undefined
[8] Departments of Neurology,undefined
[9] Brigham and Women’s Hospital,undefined
来源
Molecular Neurodegeneration | / 12卷
关键词
Alzheimer’s disease; microRNA; lincRNA; Neuritic β-amyloid plaques and neurofibrillary tangles;
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  • [1] Lambert JC(2013)Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease Nat Genet 45 1452-1458
  • [2] Ibrahim-Verbaas CA(2014)Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci Nat Neurosci 17 1156-1163
  • [3] Harold D(2013)Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease Neurobiol Aging 34 1653-1661
  • [4] Naj AC(2013)Integrative genomics identifies APOE epsilon4 effectors in Alzheimer's disease Nature 500 45-50
  • [5] Sims R(2011)β-amyloid affects frontal and posterior brain networks in normal aging NeuroImage 54 1887-1895
  • [6] Bellenguez C(2009)Amyloid deposition is associated with impaired default network function in older persons without dementia Neuron 63 178-188
  • [7] DeStafano AL(2010)Mammalian microRNAs predominantly act to decrease target mRNA levels Nature 466 835-840
  • [8] Bis JC(2009)MicroRNAs: target recognition and regulatory functions Cell 136 215-233
  • [9] Beecham GW(2011)MicroRNA regulation of homeostatic synaptic plasticity Proc Natl Acad Sci U S A 108 11650-11655
  • [10] Grenier-Boley B(2012)TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways J Neurosci 32 11213-11227