Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

被引：0
作者：
Anolin Aslan
Cynthia Aslan
Naime Majidi Zolbanin
Reza Jafari
机构：
[1] School of Nursing and Midwifery,Department of Critical Care Nursing
[2] Tehran University of Medical Science,Immunology Research Center
[3] Tabriz University of Medical Sciences,Department of Immunology
[4] Faculty of Medicine,Experimental and Applied Pharmaceutical Research Center
[5] Tabriz University of Medical Sciences,Department of Pharmacology and Toxicology
[6] Urmia University of Medical Sciences,undefined
[7] School of Pharmacy,undefined
[8] Urmia University of Medical Sciences,undefined
[9] Nephrology and Kidney Transplant Research Center,undefined
[10] Clinical Research Institute,undefined
[11] Urmia University of Medical Sciences,undefined
[12] Hematology,undefined
[13] Immune Cell Therapy,undefined
[14] and Stem Cell Transplantation Research Center,undefined
[15] Clinical Research Institute,undefined
[16] Urmia University of Medical Sciences,undefined
来源：
Pneumonia | / 13卷
关键词：
COVID-19; Acute respiratory distress syndrome; SARS-CoV-2; Pandemics; ARDS;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even though COVID-19 vaccinations are available now, there is still an urgent need to find potential treatments to ease the effects of COVID-19 on already sick patients. Multiple experimental drugs have been approved by the FDA with unknown efficacy and possible adverse effects. Probably the increasing number of studies worldwide examining the potential COVID-19 related therapies will help to identification of effective ARDS treatment. In this review article, we first provide a summary on immunopathology of ARDS next we will give an overview of management of patients with COVID-19 requiring intensive care unit (ICU), while focusing on the current treatment strategies being evaluated in the clinical trials in COVID-19-induced ARDS patients.
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