Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with post-COVID-19-syndrome (PreVitaCOV) – protocol of a randomised, double-blind, placebo-controlled multicentre trial in primary care (phase IIIb)

被引:0
作者
Caroline Tengelmann
Stefanie Joos
Yvonne Kaußner
Uwe Malzahn
Laura Lunden
Andreas Klug
Karl Georg Häusler
Catharina Escales
Walter Maetzler
Klemens Hügen
Oliver Zolk
Peter U. Heuschmann
Christian Förster
Hanna Kaduszkiewicz
Ildikó Gágyor
机构
[1] University Hospital Würzburg,Department of General Practice
[2] University Hospital Tübingen,Institute of General Practice and Interprofessional Care
[3] University Hospital Würzburg,Clinical Trial Center
[4] University of Kiel,Institute of General Practice
[5] University Hospital Würzburg,Department of Neurology
[6] University Hospital Schleswig-Holstein,Department of Neurology
[7] Immanuel Klinik Rüdersdorf,Institute of Clinical Pharmacology, Brandenburg Medical School, Faculty of Health Sciences Brandenburg
来源
BMC Infectious Diseases | / 24卷
关键词
Post-COVID-19-Syndrome; Prednisolone; Vitamin B; Primary care; Randomised controlled trial;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 40 条
  • [1] Nehme M(2021)COVID-19 symptoms: longitudinal evolution and persistence in outpatient settings Ann Intern Med 174 723-5
  • [2] Crook H(2021)Long covid-mechanisms, risk factors, and management BMJ 374 n1648-74
  • [3] Förster C(2022)Persisting symptoms after COVID-19 Dtsch Arztebl Int 119 167-64
  • [4] Al-Aly Z(2021)High-dimensional characterization of post-acute sequelae of COVID-19 Nature 594 259-4
  • [5] Xie Y(2021)Assessment of the frequency and Variety of persistent symptoms among patients with COVID-19: a systematic review JAMA Netw Open 4 e2111417-82
  • [6] Bowe B(2022)Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2 Lancet 399 2263-54
  • [7] Nasserie T(2022)Post-acute sequelae of covid-19 six to 12 months after Infection: population based study BMJ 379 e071050-85
  • [8] Hittle M(2021)Characterizing long COVID in an international cohort: 7 months of symptoms and their impact EClinicalMedicine 38 101019-13
  • [9] Goodman SN(2021)Post-acute effects of SARS-CoV-2 Infection in individuals not requiring hospital admission: a Danish population-based cohort study Lancet Infect Dis 21 1373-8
  • [10] Antonelli M(2021)Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments Infect Dis (Lond) 53 737-61