The Effects of Phrenic Nerve Degeneration by Axotomy and Crush on the Electrical Activities of Diaphragm Muscles of Rats

被引：0
作者：
Mehmet Eşref Alkiş
Servet Kavak
Fuat Sayır
Aydin Him
机构：
[1] Muş Alparslan University,Vocational College Technical Programmes
[2] Muğla Sıtkı Koçman University,Department of Biophysics, Faculty of Medicine
[3] Yüzüncü Yıl University,Department of Thoracic Surgery, Faculty of Medicine
[4] Ondokuzmayis University,Department of Biophysics
[5] Medical School,undefined
来源：
Cell Biochemistry and Biophysics | 2016年 / 74卷
关键词：
Electro-biophysics; Phrenic nerves; Diaphragm muscle; Rats;
D O I：
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中图分类号：
学科分类号：
摘要：
The aim of this study was to investigate the effect of axotomy and crush-related degeneration on the electrical activities of diaphragm muscle strips of experimental rats. In the present study, twenty-one male Wistar-albino rats were used and divided into three groups. The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Resting membrane potential (RMP) was decreased significantly in both crush and axotomy of diaphragm muscle strips of experimental rats (p < 0.05). Depolarization time (TDEP) and half-repolarization (1/2 RT) time were significantly prolonged in crush and axotomy rats (p < 0.05). Crushing or axotomizing the phrenic nerves may produce electrical activities in the diaphragm muscle of the rat by depolarization time and half-repolarization time prolonged in crush and axotomy rats.
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页码：29 / 34
页数：5
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