Binding varicella zoster virus: an underestimated facet of insulin-degrading enzyme´s implication for Alzheimer´s disease pathology?

被引:0
作者
Hans-Gert Bernstein
Gerburg Keilhoff
Henrik Dobrowolny
Johann Steiner
机构
[1] University of Magdeburg,Department of Psychiatry and Psychotherapy, Medical Faculty
[2] University of Magdeburg,Medical Faculty, Institute of Biochemistry and Cell Biology
[3] Otto-von-Guericke University Magdeburg,Department of Psychiatry
来源
European Archives of Psychiatry and Clinical Neuroscience | 2020年 / 270卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
We shortly discuss a possible contribution of insulin-degrading enzyme to Alzheimer´s disease pathology by binding varicella zoster virus glycoprotein E, which increases the infectivity and cell–cell spread of the virus.
引用
收藏
页码:495 / 496
页数:1
相关论文
共 61 条
  • [1] Bernstein HG(1999)Insulin-degrading enzyme in the Alzheimer’s disease brain: prominent localization in neurons and senile plaques Neurosci Lett 263 161-164
  • [2] Ansorge S(2018)Insulin-degrading enzyme in the fight against Alzheimer’s disease Trends Pharmacol Sci 39 49-58
  • [3] Riederer P(2016)Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer’s disease? Ann Med 48 614-624
  • [4] Reiser M(2018)Corroboration of a major role for Herpes Simplex Virus Type 1 in Alzheimer’s disease Front Aging Neurosci 10 324-271
  • [5] Frölich L(2003)Herpesviruses in brains in Alzheimer’s and Parkinson’s diseases Ann Neurol 54 267-1424
  • [6] Bogerts B(2017)Increased risk of dementia following herpes zoster ophthalmicus PLoS One 12 e0188490-316
  • [7] Kurochkin IV(2018)Herpes zoster and dementia J Clin Psychiatry 79 16 m11312-56
  • [8] Guarnera E(2017)On the role of infection in Alzheimer´s disease (AD): Herpes viruses areassociated with significant increase in AD risk in a large population—representative sample of eldery individuals Alzheimer’s Dement 13 1423-undefined
  • [9] Berezovsky IN(2006)Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread Cell 127 305-undefined
  • [10] Pivovarova O(2010)Insulin degrading enzyme induces a conformational change in Varicella-Zoster Virus gE, and enhances virus infectivity and stability PLoS One 5 e11327-undefined