Structural studies and antimicrobial properties of norcembrane diterpenoid from an Indian soft coral Sinularia inelegans Tixier-Durivault

被引：0
作者：
Keisham Sarjit Singh
Werner H. Kaminsky
Celina Rodrigues
C. G. Naik
机构：
[1] National Institute of Oceanography (CSIR),Bioorganic Chemistry Laboratory
[2] University of Washington,Department of Chemistry
来源：
Journal of Chemical Sciences | 2009年 / 121卷
关键词：
Diterpene; sinularia; stereochemistry; antimicrobial; crystallography;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two metabolites featuring norcembranoid diterpene skeleton have been isolated from chloroform extract of soft coral of the genus sinularia, which was collected from the southern coast of India. The structures of the metabolites were determined by 1D, 2D NMR spectroscopic data and HRESIMS data analysis. The compounds have shown moderate-to-high antimicrobial activities. The structure and the relative stereochemistry of the metabolite 1 have been determined by X-ray crystallography.
引用
收藏
页码：1041 / 1046
页数：5
相关论文
共 109 条
  • [1] Gokdshlager G. K.(1996)undefined J. Nat. Prod. 59 262-undefined
  • [2] Klein P.(1981)undefined Aust. J. Chem. 34 1551-undefined
  • [3] Rudi A.(2005)undefined J. Nat. Prod. 68 649-undefined
  • [4] Banyahu Y.(2005)undefined Biol. Pharm. Bull. 28 1311-undefined
  • [5] Schleyer M.(2005)undefined J. Nat. Prod. 65 1087-undefined
  • [6] Kashman Y.(2006)undefined Tetrahedron Lett. 47 2937-undefined
  • [7] Bowden B. F.(2005)undefined Org. Lett. 7 3813-undefined
  • [8] Coll J. C.(1997)undefined Tetrahedron 53 4569-undefined
  • [9] Mitchell S. J.(1999)undefined Nat. Prod. Rep. 16 155-undefined
  • [10] Kazlauskas R.(2000)undefined Nat. Prod. Rep. 17 7-undefined
12345678910