Epstein-Barr virus infection: the micro and macro worlds

被引:0
作者
Wei Huang
Lang Bai
Hong Tang
机构
[1] West China Hospital of Sichuan University,Center of Infectious Diseases
[2] Sichuan University,Division of Infectious Diseases, State Key Laboratory of Biotherapy and Center of Infectious Diseases, West China Hospital
来源
Virology Journal | / 20卷
关键词
Immune response; Immune escape; EBV-associated diseases; Epstein‒Barr virus;
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学科分类号
摘要
Epstein‒Barr virus (EBV) is a DNA virus that belongs to the human B lymphotropic herpesvirus family and is highly prevalent in the human population. Once infected, a host can experience latent infection because EBV evades the immune system, leading to hosts harboring the virus for their lifetime. EBV is associated with many diseases and causes significant challenges to human health. This review first offers a description of the natural history of EBV infection, clarifies the interaction between EBV and the immune system, and finally focuses on several major types of diseases caused by EBV infection.
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[1]  
Epstein MA(1964)VIRUS PARTICLES IN CULTURED LYMPHOBLASTS FROM BURKITT’S LYMPHOMA Lancet 1 702-3
[2]  
Achong BG(2011)Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States Blood 117 5835-49
[3]  
Barr YM(2022)Epstein-Barr virus: Biology and clinical disease Cell 185 3652-70
[4]  
Cohen JI(2004)Epstein-Barr Virus and Cancer Clin Cancer Res 10 803-21
[5]  
Jaffe ES(1990)Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3 C genes J Virol 64 4084-92
[6]  
Dale JK(2008)Differential gene regulation by Epstein-Barr virus type 1 and type 2 EBNA2 J Virol 82 7456-66
[7]  
Pittaluga S(2015)Epstein-Barr virus type 2 latently infects T cells, inducing an atypical activation characterized by expression of lymphotactic cytokines J Virol 89 2301-12
[8]  
Heslop HE(1986)Geographical prevalence of two types of Epstein-Barr virus Virology 154 56-66
[9]  
Rooney CM(2000)Epstein-Barr virus infection N Engl J Med 343 481-92
[10]  
Damania B(2014)Epstein-Barr virus (EBV) infection in chinese children: a retrospective study of age-specific prevalence PLoS ONE 9 e99857-22