Molecular etiological profile of atypical bacterial pathogens, viruses and coinfections among infants and children with community acquired pneumonia admitted to a national hospital in Lima, Peru

被引：16

作者：

Del Valle-Mendoza J. ^{[1
,2
]}

Silva-Caso W. ^{[1
,2
]}

Cornejo-Tapia A. ^{[1
]}

Orellana-Peralta F. ^{[1
]}

Verne E. ^{[3
]}

Ugarte C. ^{[3
]}

Aguilar-Luis M.A. ^{[1
,2
]}

De Lama-Odría M.D.C. ^{[1
]}

Nazario-Fuertes R. ^{[2
]}

Esquivel-Vizcarra M. ^{[2
]}

Casabona-Ore V. ^{[1
]}

Weilg P. ^{[1
]}

Del Valle L.J. ^{[4
]}

机构：

[1] School of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Av. San Marcos cdra. 2. Cedros de Villa, Chorrillos, Lima

[2] Instituto de Investigación Nutricional, Av. La Molina 1885

[3] Hospital Nacional Cayetano Heredia, Lima

[4] Barcelona Research Center for Multiscale Science and Engineering, Departament d'Enginyeria Qulímica, EEBE, Universitat Politècnica de Catalunya (UPC), Barcelona Tech, C/Eduard Maristany, 10-14, Ed. I2, Barcelona

来源：

BMC Research Notes | / 10卷 / 1期

关键词：

Atypical pathogens; CAP; Community-acquired pneumonia; Respiratory infection; Respiratory viruses;

D O I：

10.1186/s13104-017-3000-3

中图分类号：

学科分类号：

摘要：

Objective: The main objective of this study was to detect the presence of 14 respiratory viruses and atypical bacteria (Mycoplasma pneumoniae, Chlamydia pneumoniae), via polymerase chain reaction in patients under 18 years old hospitalized due to community-acquired pneumonia (CAP) from Lima, Peru. Results: Atypical pathogens were detected in 40% (58/146); viral etiologies in 36% (52/146) and coinfections in 19% (27/146). The most common etiological agent was M. pneumoniae (n = 47), followed by C. pneumoniae (n = 11). The most frequent respiratory viruses detected were: respiratory syncytial virus A (n = 35), influenza virus C (n = 21) and parainfluenza virus (n = 10). Viral-bacterial and bacterium-bacterium coinfections were found in 27 cases. In our study population, atypical bacteria (40%) were detected as frequently as respiratory viruses (36%). The presence of M. pneumoniae and C. pneumoniae should not be underestimated as they can be commonly isolated in Peruvian children with CAP. © 2017 The Author(s).

引用

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