The Utility of Prostate-Specific Antigen Screening and Prostate Cancer Treatment in Elderly Patients

被引：0
|
作者：
Annelies Vellekoop
Stacy Loeb
机构：
[1] New York University (AV,Department of Urology
[2] SL) and Manhattan Veterans Affairs Medical Center (SL),undefined
来源：
Current Translational Geriatrics and Experimental Gerontology Reports | 2013年 / 2卷 / 2期
关键词：
Prostate cancer; Screening; Elderly; Comorbidity; Treatment; Survival;
D O I：
10.1007/s13670-013-0041-x
中图分类号：
学科分类号：
摘要：
Screening and treatment of prostate cancer remain controversial, particularly for elderly men. Since the previous United States Preventive Services Task Force recommendation in 2008 against prostate-specific antigen (PSA) screening after age 75 years, there has not been a substantial reduction in the frequency of PSA testing in this age group. A substantial proportion of elderly men are overdiagnosed and overtreated. On the other hand, men aged >75 years have more aggressive disease. Although screening has questionable benefit for elderly men with significant comorbidities, healthy men >75 years may benefit from definitive therapy. This review discusses prostate cancer screening and management decisions for elderly men, including the use of nomograms and predictive tools for life expectancy.
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页码：51 / 57
页数：6
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