Is sodium chloride worth its salt?

被引：0
作者：
Euan McIntosh
Peter J Andrews
机构：
[1] Royal Infirmary of Edinburgh,Department of Anaesthesia & Critical Care
[2] NHS Lothian,undefined
[3] The Army Medical Corps,undefined
[4] Centre for Clinical Brain Sciences,undefined
[5] The University of Edinburgh,undefined
[6] NHS Lothian,undefined
[7] Western General Hospital,undefined
来源：
Critical Care | / 17卷
关键词：
Intracranial Hypertension; Cerebral Perfusion Pressure; Sodium Chloride Solution; Hydroxyethyl Starch; Acute Brain Injury;
D O I：
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摘要：
The choice of fluid for resuscitation of the brain-injured patient remains controversial, and the 'ideal' resuscitation fluid has yet to be identified. Large volumes of hypotonic solutions must be avoided because of the risk of cerebral swelling and intracranial hypertension. Traditionally, 0.9% sodium chloride has been used in patients at risk of intracranial hypertension, but there is increasing recognition that 0.9% saline is not without its problems. Roquilly and colleagues show a reduction in the development of hyperchloremic acidosis in brain-injured patients given 'balanced' solutions for maintenance and resuscitation compared with 0.9% sodium chloride. In this commentary, we explore the idea that we should move away from 0.9% sodium chloride in favor of a more 'physiological' solution.
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