Composition and Structure of Gut Microbiome in Adolescents with Obesity and Different Breastfeeding Duration

被引：0
作者：
N. L. Belkova
U. M. Nemchenko
A. V. Pogodina
S. I. Feranchuk
A. I. Romanitsa
E. A. Novikova
L. V. Rychkova
机构：
[1] Research Center for Family Health and Human Reproduction Problems,
[2] Limnological Institute,undefined
[3] Siberian Division of the Russian Academy of Sciences,undefined
[4] Irkutsk National Research Technical University,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2019年 / 167卷
关键词：
gut microbiome; obesity; adolescents; breastfeeding;
D O I：
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学科分类号：
摘要：
Gut microbiome of adolescents with obesity and different duration of breastfeeding was analyzed by metagenomic analysis of V3-V4 variable domains of the 16S rRNA gene. In subgroup with breastfeeding duration <3 months, intrapopulation structure of gut microbiome by alpha diversity indices was similar in adolescents with obesity and normal body weight. The decrease in phylotype abundance in the structure of communities was associated only with obesity, while dysbiotic state persisted in both lean and overweight adolescents, which confirmed the effect of breastfeeding duration on stability of gut microbiome.
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页码：759 / 762
页数：3
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