Bilateral rectus sheath haematoma complicating dengue virus infection in a patient on warfarin for mechanical aortic valve replacement: A case report

被引:2
作者
Rosa C.T. [1 ]
Navinan M.R. [2 ]
Samarawickrama S. [1 ]
Hamza H. [1 ]
Gunarathne M. [1 ]
Arulanantham A. [1 ]
Subba N. [1 ]
Samarasiri U. [1 ]
Mathias T. [1 ]
Kulatunga A. [1 ]
机构
[1] Internal Medicine, National Hospital of Sri Lanka, Colombo
[2] Institute of Cardiology, National Hospital of Sri Lanka, Colombo
关键词
Anticoagulation; Bleeding; Case report; Dengue viral fever; Haematoma; Mechanical valves; Rectus sheath; Warfarin;
D O I
10.1186/s13104-016-2330-x
中图分类号
学科分类号
摘要
Background: The management of Dengue virus infection can be challenging. Varied presentations and numerous complications intrinsic to dengue by itself increase the complexity of treatment and potential mortality. When burdened with the presence of additional comorbidities and the need to continue compulsory medications, clear stepwise definitive guidance is lacking and patients tend to have more complex complications and outcomes calling to question the clinical decisions that may have been taken. The use and continuation of warfarin in dengue virus infection is one such example. Case presentation: We report a 65 year old South Asian female who presented with dengue fever. She had a history bronchial asthma, a prior abdominal surgery, and was on warfarin and maintained a therapeutically appropriate internationalized normalized ratio for a mechanical aortic valve replacement. Though preemptive decision to stop warfarin was taken with decreasing platelet counts, her clinical course was complicated with the development of bilateral rectus sheath haematoma's requiring resuscitation with blood transfusions. Conclusion: Though management of dengue viral fever has seen drastic evolution with recent updated guidance, clinical scenarios seen in the course of the illness still pose challenges to the managing physician. The need to continue obligatory anticoagulation which may seem counterintuitive during a complex disease such as dengue virus infection must be considered after understanding the potential risks versus that of its benefits. Though case by case decisions maybe warranted, a clear protocol would be very helpful in making clinical decisions, as the correct preemptive decision may potentially avert catastrophic and unpredictable bleeding events. © 2017 The Author(s).
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  • [1] Dengue and Severe Dengue: Fact Sheet No. 117. In: Dengue and Severe Dengue, (2015)
  • [2] Villar L., Dayan G.H., Arredondo-Garcia J.L., Rivera D.M., Cunha R., Deseda C., Et al., Efficacy of a tetravalent dengue vaccine in children in Latin America, N Engl J Med, 372, 2, pp. 113-123, (2015)
  • [3] Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Haemorrhagic Fever: Revised and Expanded Edition, (2011)
  • [4] Kalayanarooj S., Clinical manifestations and management of Dengue/DHF/DSS, Trop Med Health, 39, 4, pp. 83-87, (2011)
  • [5] Lim T.S.H., Grignani R.T., Tambyah P.A., Quek S.C., Impact of dengue-induced thrombocytopenia on mandatory anticoagulation for patients with prosthetic heart valves on warfarin, Singap Med J, 56, 4, pp. 235-236, (2015)
  • [6] Srichaikul T., Nimmannitya S., Haematology in dengue and dengue haemorrhagic fever, Bailliere's Best Pract Res Clin Haematol, 13, 2, pp. 261-276, (2000)
  • [7] Sellahewa K.H., Pathogenesis of dengue haemorrhagic fever and its impact on case management, ISRN Infect Dis, 2013, (2013)
  • [8] Pesaro A.E., D'Amico E., Aranha L.F.C., Dengue: Manifestações cardíacas e implicações na terapêutica antitrombótica, Arq Bras Cardiol, 89, pp. e12-e15, (2007)
  • [9] Borosak M., Choo S., Street A., Warfarin: Balancing the benefits and harms, Aust Prescr, 27, 4, pp. 88-92, (2004)
  • [10] Patient Information: Warfarin (Coumadin) (Beyond the Basics) [Database on the Internet], (2016)