What has changed with riluzole?

被引:0
|
作者
V. Meininger
L. Lacomblez
F. Salachas
机构
[1] Fédération de Neurologie Mazarin,
[2] Division Mazarin,undefined
[3] Hôpital de la Salpêtrière,undefined
[4] 47 boulevard de l'Hôpital,undefined
[5] 75013 Paris,undefined
[6] France,undefined
[7] e-mail: vincent.meininger@psl.ap-hop-paris.fr,undefined
关键词
Key words riluzole; sodium channel; glutamate; therapeutic trials;
D O I
10.1007/PL00007784
中图分类号
学科分类号
摘要
Riluzole, after two significant trials, was introduced as the first standard treatment of amyotrophic lateral clerosis (ALS) in the early 95'. After 5 years what has changed in the field of ALS?
引用
收藏
页码:VI19 / VI22
相关论文
共 50 条
  • [31] Mechanism of Neuroprotection Against Experimental Spinal Cord Injury by Riluzole or Methylprednisolone
    Cynthia Sámano
    Andrea Nistri
    Neurochemical Research, 2019, 44 : 200 - 213
  • [32] Effect of chronic treatment with riluzole on the nigrostriatal dopaminergic system in weaver mutant mice
    Douhou, A
    Debeir, T
    Murer, MG
    Do, L
    Dufour, N
    Blanchard, V
    Moussaoui, S
    Bohme, GA
    Agid, Y
    Raisman-Vozari, R
    EXPERIMENTAL NEUROLOGY, 2002, 176 (01) : 247 - 253
  • [33] ANESTHETIC PROPERTIES OF RILUZOLE (54274-RP), A NEW INHIBITOR OF GLUTAMATE NEUROTRANSMISSION
    MANTZ, J
    CHERAMY, A
    THIERRY, AM
    GLOWINSKI, J
    DESMONTS, JM
    ANESTHESIOLOGY, 1992, 76 (05) : 844 - 848
  • [34] Combination Of Riluzole And Rivastigmine- A Potential Treatment Strategy For Alzheimer?s Disease
    Narendar, Chintha
    Tharani, M.
    Rao, Gaddam Narasimha
    Raj, M. Anvesh
    Justin, Antony
    JOURNAL OF POPULATION THERAPEUTICS AND CLINICAL PHARMACOLOGY, 2023, 30 (04): : E316 - E327
  • [35] New insight into the effect of riluzole on cadmium tolerance and accumulation in duckweed (Lemna turionifera)
    Yang, Lin
    Ren, Qiuting
    Ma, Xu
    Wang, Mingwei
    Sun, Jinge
    Wang, Shen
    Wu, Xiaoyu
    Chen, Xinglin
    Wang, Chenxin
    Li, Qingqing
    Sun, Jinsheng
    ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2022, 241
  • [36] Hippocampal N-acetylaspartate concentration and response to riluzole in generalized anxiety disorder
    Mathew, Sanjay J.
    Price, Rebecca B.
    Mao, Xangling
    Smith, Eric L. P.
    Coplan, Jeremy D.
    Charney, Dennis S.
    Shungu, Dikoma C.
    BIOLOGICAL PSYCHIATRY, 2008, 63 (09) : 891 - 898
  • [37] Riluzole Exhibits No Therapeutic Efficacy on a Transgenic Rat model of Amyotrophic Lateral Sclerosis
    Chen, Si
    Liao, Qiao
    Lu, Ke
    Zhou, Jinxia
    Huang, Cao
    Bi, Fangfang
    CURRENT NEUROVASCULAR RESEARCH, 2020, 17 (03) : 275 - 285
  • [38] Riluzole does not improve lifespan or motor function in three ALS mouse models
    Hogg, Marion C.
    Halang, Luise
    Woods, Ina
    Coughlan, Karen S.
    Prehn, Jochen H. M.
    AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2018, 19 (5-6) : 438 - 445
  • [39] Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice
    Del Signore, Steven J.
    Amante, Daniel J.
    Kim, Jinho
    Stack, Edward C.
    Goodrich, Sarah
    Cormier, Kerry
    Smith, Karen
    Cudkowicz, Merit E.
    Ferrante, Robert J.
    AMYOTROPHIC LATERAL SCLEROSIS, 2009, 10 (02): : 85 - 94
  • [40] Riluzole: a therapeutic strategy in Alzheimer's disease by targeting the WNT/β-catenin pathway
    Vallee, Alexandre
    Vallee, Jean-Noel
    Guillevin, Remy
    Lecarpentier, Yves
    AGING-US, 2020, 12 (03): : 3095 - 3113