Circulating Bone Marrow Osteoclast Precursors and Osteoclastogenesis in Patients with Type IIA and IIB Hyperlipidemias

被引：0
|
作者：
E. L. Soboleva
O. S. Saburova
T. A. Rozhkova
机构：
[1] Russian Ministry of Health,Laboratory of Molecular and Cellular Cardiology, Institute of Experimental Cardiology
[2] Russian Ministry of Health,Laboratory of Hemodialysis and Plasmapheresis, Institute of Clinical Cardiology, Russian Research
来源：
Bulletin of Experimental Biology and Medicine | 2001年 / 132卷
关键词：
hyperlipidemia; osteoclastogenesis; calcium; osteoporosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Osteoclasts, the major source of calcium released during bone resorption, and their precursors preosteoclasts derive from bone marrow hemopoietic stem cells, granulocyte-macrophage colony-forming units. The factors responsible for commitment of colony-forming units into osteoclast precursors remain unknown. Studies of osteoclastogenesis in cultured blood mononuclear cells from patients with hyperlipidemia accompanied by atherosclerosis and calcification of vessels revealed high content of preosteoclasts in the blood.
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页码：890 / 894
页数：4
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