Metabolic effects of high-protein diets

被引:36
作者
Clifton P.M. [1 ]
Keogh J. [1 ]
机构
[1] CSIRO Human Nutrition, Adelaide BC, SA 5000
关键词
Lean Mass; Weight Loss Study; Atkins Diet; High Glycemic Load; Zone Diet;
D O I
10.1007/s11883-007-0063-y
中图分类号
学科分类号
摘要
Protein is more satiating than carbohydrate or fat, and high-protein diets (25%-35% of energy) are commonly used for weight loss. High-protein diets usually replace carbohydrate with protein and may be low or high in saturated fat. Invariably, serum triglyceride is lower with the lower intake of carbohydrate, but the effects on high-density lipoprotein cholesterol and low-density lipoprotein cholesterol are strongly dependent on the amount of carbohydrate restriction and the intake of saturated fat, and in some cases low-density lipoprotein cholesterol may rise despite weight loss. In situations of weight stability, higher intakes of protein are associated with lower blood pressures, and in diabetic patients higher intakes of protein are associated with lower glycosylated hemoglobin. The overall effect on long-term atherosclerosis risk is not clear, as the current limited epidemiology provides conflicting data. Copyright © 2007 by Current Medicine Group LLC.
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页码:472 / 478
页数:6
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共 44 条
[1]  
Hu F.B., Stampfer M.J., Manson J.E., Et al., Dietary protein and risk of ischemic heart disease in women, Am J Clin Nutr, 70, pp. 221-227, (1999)
[2]  
Iso H., Stampfer M.J., Manson J.E., Et al., Prospective study of fat and protein intake and risk of intraparenchymal hemorrhage in women, Circulation, 103, pp. 856-863, (2001)
[3]  
Kelemen L.E., Kushi L.H., Jacobs Jr D.R., Cerhan J.R., Associations of dietary protein with disease and mortality in a prospective study of postmenopausal women, Am J Epidemiol, 161, pp. 239-249, (2005)
[4]  
Snowdon D.A., Phillips R.L., Fraser G.E., Meat consumption and fatal ischemic heart disease, Prev Med, 13, pp. 490-500, (1984)
[5]  
Skov A.R., Toubro S., Ronn B., Et al., Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity, Int J Obes Relat Metab Disord, 23, pp. 528-536, (1999)
[6]  
Due A., Toubro S., Skov A.R., Astrup A., Effect of normal-fat diets, either medium or high in protein, on body weight in overweight subjects: A randomised 1-year trial, Int J Obes Relat Metab Disord, 28, pp. 1283-1290, (2004)
[7]  
McAuley K.A., Hopkins C.M., Smith K.J., Et al., Comparison of high-fat and high-protein diets with a high-carbohydrate diet in insulin-resistant obese women, Diabetologia, 48, pp. 8-16, (2005)
[8]  
Gardner C.D., Kiazand A., Alhassan S., Et al., Comparison of the Atkins, Zone, Ornish, and LEARN diets for change in weight and related risk factors among overweight premenopausal women: The A TO Z Weight Loss Study: a randomized trial, JAMA, 297, pp. 969-977, (2007)
[9]  
Dansinger M.L., Gleason J.A., Griffith J.L., Et al., Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: A randomized trial, JAMA, 293, pp. 43-53, (2005)
[10]  
Weigle D.S., Breen P.A., Matthys C.C., Et al., A high-protein diet induces sustained reductions in appetite, ad libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghrelin concentrations, Am J Clin Nutr, 82, pp. 41-48, (2005)