Targeting DNA repair and the cell cycle in glioblastoma

被引：0

作者：

Brian M. Alexander

Nancy Pinnell

Patrick Y. Wen

Alan D’Andrea

机构：

[1] Dana-Farber/Brigham and Women’s Cancer Center,Department of Radiation Oncology

[2] Harvard Medical School,Department of Neurology

[3] Dana-Farber/Brigham and Women’s Cancer Center,undefined

[4] Harvard Medical School,undefined

来源：

Journal of Neuro-Oncology | 2012年 / 107卷

关键词：

DNA repair; Cell cycle; Glioblastoma;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Glioblastoma is a disease with poor outcomes despite standard therapy. Specific targeting of the DNA damage response is a strategy that is becoming increasingly employed in oncology and has intriguing potential for improving outcomes in glioblastoma. DNA damage targeting has implications for improving current therapy as well as the potential to leverage inherent differences in glioblastoma cells to widen the therapeutic window.

引用

页码：463 / 477

页数：14

共 50 条

[1] Targeting DNA repair and the cell cycle in glioblastoma
Alexander, Brian M.
Pinnell, Nancy
Wen, Patrick Y.
D'Andrea, Alan
JOURNAL OF NEURO-ONCOLOGY, 2012, 107 (03) : 463 - 477
[2] Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma
Brockelmann, Paul J.
de Jong, Mathilde R. W.
Jachimowicz, Ron D.
CELLS, 2020, 9 (10)
[3] DNA REPAIR The cell cycle flavours of repair
Zlotorynski, Eytan
NATURE REVIEWS GENETICS, 2016, 17 (02) : 65 - 65
[4] Targeting the cell cycle to enhance chemotherapy efficacy in glioblastoma
McCord, Matthew
Jamshidi, Pouya
NEURO-ONCOLOGY, 2024, 26 (06) : 1097 - 1098
[5] The cell cycle and DNA mismatch repair
Schroering, Allen G.
Edelbrock, Michael A.
Richards, Timothy J.
Williams, Kandace J.
EXPERIMENTAL CELL RESEARCH, 2007, 313 (02) : 292 - 304
[6] The control of DNA repair by the cell cycle
Nicole Hustedt
Daniel Durocher
Nature Cell Biology, 2017, 19 : 1 - 9
[7] The control of DNA repair by the cell cycle
Hustedt, Nicole
Durocher, Daniel
NATURE CELL BIOLOGY, 2017, 19 (01) : 1 - 9
[8] CELL CYCLE REGULATION OF THE DNA DAMAGE RESPONSE: TARGETING WEE1 KINASE TO IMPAIR DNA REPAIR
Van Vugt, M. A. T. M.
Krajewska, M.
Sillje, H.
Heijink, A. M.
Bisselink, Y.
de Vries, E. G. E.
RADIOTHERAPY AND ONCOLOGY, 2012, 104 : 21 - 21
[9] Regulation of DNA repair throughout the cell cycle
Dana Branzei
Marco Foiani
Nature Reviews Molecular Cell Biology, 2008, 9 : 297 - 308
[10] Integrating DNA damage repair with the cell cycle
Murray, Johanne M.
Carr, Antony M.
CURRENT OPINION IN CELL BIOLOGY, 2018, 52 : 120 - 125

← 1 2 3 4 5 →