Mesalazine-induced myopericarditis in a patient with ulcerative colitis

被引：7

作者：

Asadi J. ^{[1
]}

Bhandari S.S. ^{[1
]}

Ahmed N. ^{[1
]}

机构：

[1] Department of Cardiology, Royal Derby Hospital, Derby Hospital NHS Foundation Trust, Derby

来源：

Echo Research & Practice | 2018年 / 5卷 / 1期

关键词：

F magnetic resonance imaging f echocardiography f mesalazine f myopericarditis f myocarditis;

D O I：

10.1530/ERP-17-0044

中图分类号：

学科分类号：

摘要：

A 25-year-old male with a background of ulcerative colitis presented with a two-week history of central chest pain. His ECG on presentation showed global T wave inversion with a peak troponin I of 165ng/mL. Clinical diagnosis of myopericarditis/myocarditis was made. Echocardiography and cardiac magnetic resonance (MR) confirmed the diagnosis. On detailed assessment of his medication history, mesalazine was suspected as an etiological factor, with discontinuation resulting in an improvement in symptoms, inflammatory markers and cardiac enzymes. This is a unique case of mesalazine-induced myopericarditis on a background of inflammatory bowel disease. © 2018 The authors.

引用

页码：K1 / K5

页数：4

共 9 条

[1]

Liu P.P., Mason J.W., Advances in the understanding of myocarditis, Circulation, 104, pp. 1076-1082, (2001)

[2]

Freeman H.J., Salh B., Recurrent myopericarditis with extensive ulcerative colitis, Canadian Journal of Cardiology, 26, pp. 549-550, (2010)

[3]

Mahrholdt H., Goedecke C., Wagner A., Meinhardt G., Athanasiadis A., Vogelsberg H., Fritz P., Klingel K., Kandolf R., Sechtem U., Cardiovascular magnetic resonance assessment of human myocarditis: A comparison to histology and molecular pathology, Circulation, 109, pp. 1250-1258, (2004)

[4]

Friedrich M.G., Sechtem U., Schulz-Menger J., Holmvang G., Alakija P., Cooper L.T., White J.A., Abdel-Aty H., Gutberlet M., Prasad S., Et al., Cardiovascular magnetic resonance in myocarditis: A JACC white paper, JACC, 53, pp. 1475-1487, (2009)

[5]

Abdel-Aty H., Boye P., Zagrosek A., Wassmuth R., Kumar A., Messroghli D., Bock P., Dietz R., Friedrich M.G., Schulz-Menger J., Diagnostic performance of cardiovascular magnetic resonance in patients with suspected acute myocarditis, JACC, 45, pp. 1815-1822, (2005)

[6]

Caforio A.L.P., Pankuweit S., Arbustini E., Basso C., Gimeno-Blanes J., Felix S.B., Fu M., Helio T., Heymans S., Jahns R., Et al., Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: A position statement of the european society of cardiology working group on myocardial and pericardial diseases, European Heart Journal, 34, pp. 2636-2648, (2013)

[7]

Kindermann I., Barth C., Mahfoud F., Ukena C., Lenski M., Yilmaz A., Klingel K., Kandolf R., Sechtem U., Cooper L.T., Et al., Update on myocarditis, JACC, 59, pp. 779-792, (2012)

[8]

Katsanos K.H., Tsianos E.V., The heart in inflammatory bowel disease, Annals of Gastroenterology, 15, pp. 124-133, (2002)

[9]

Lacucci M., De Silva S., Ghosh S., Mesalazine in inflammatory bowel disease: A trendy topic again?, Canadian Journal of Gastroenterology, 24, pp. 127-133, (2010)

← 1 →