Pollen Typhae Total Flavone Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis in Human Aortic-Vascular Smooth Muscle Cells through Down-Regulating PERK-eIF2α-ATF4-CHOP Pathway

被引:0
作者
Ming-tai Chen
Ruo-lan Huang
Li-jun Ou
Ying-nan Chen
Ling Men
Xiao Chang
Ling Wang
Yu-zhu Yang
Zhong Zhang
机构
[1] Guangzhou University of Traditional Chinese Medicine,Cardiovascular Department, Shenzhen Traditional Chinese Medicine Hospital
来源
Chinese Journal of Integrative Medicine | 2019年 / 25卷
关键词
total flavone; endoplasmic reticulum stress; protein kinase RNA-like endoplasmic reticulum kinase-eukaryotic translation initiation factor 2α-activating transcription factor 4-CCAAT/enhancer binding protein homologous protein pathway; apoptosis; vulnerable atherosclerotic plaque;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:604 / 612
页数:8
相关论文
共 127 条
  • [1] Libby P(2002)Stabilization of atherosclerotic plaques: new mechanisms and clinical targets Nature Med 8 1257-1262
  • [2] Aikawa M(1989)Circadian variation and triggers of onset of acute cardiovascular disease Circulation 79 733-743
  • [3] Muller JE(2010)Concept of vulnerable/unstable plaque Arterioscler Thromb Vasc Biol 30 1282-1292
  • [4] Tofler GH(1997)Coronary risk factors and plaque morphology in men with coronary disease who died suddenly N Engl J Med 336 1276-1282
  • [5] Stone PH(2011)Progress and challenges in translating the biology of atherosclerosis Nature 473 317-325
  • [6] Finn AV(2011)Atherosclerosis: current pathogenesis and therapeutic options Nature Med 17 1410-1422
  • [7] Nakano M(2013)Vascular smooth muscle cell sirtuin 1 protects against DNA damage and inhibits atherosclerosis Circulation 127 386-396
  • [8] Narula J(2006)Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis Nature Med 12 1075-1080
  • [9] Kolodgie FD(1999)Role of smooth muscle cell death in advanced coronary primary lesions: implications for plaque instability Cardiovasc Res 41 480-488
  • [10] Virmani R(2008)Chronic apoptosis of vascular smooth muscle cells accelerates atherosclerosis and promotes calcification and medial degeneration Circ Res 102 1529-1538