Serum Resistin Levels May Contribute to an Increased Risk of Acute Cerebral Infarction

被引:0
作者
Xiao-Liu Dong
Shi-Jun Xu
Li Zhang
Xiu-Qing Zhang
Ting Liu
Qiu-Yan Gao
Qing-Qiang Qian
Bao-Liang Sun
Ming-Feng Yang
机构
[1] Tangshan People’s Hospital,Department of Neurology
[2] Tangshan People’s Hospital,Department of Neurosurgery
[3] Tangshan People’s Hospital,Department of Ultrasonic Medicine
[4] Affiliated Tangshan Gongren Hospital of North China University of Science and Technology,Department of Neurology
[5] Taishan Medical University,Key Lab of Cerebral Microcirculation in Universities of Shandong
来源
Molecular Neurobiology | 2017年 / 54卷
关键词
Resistin; Acute cerebral infarction; Acute stroke; Acute cerebrovascular disease; Found in inflammatory zone 3; Adipocyte-specific secretory factor;
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摘要
The objective of this study was to investigate the association between serum resistin levels and acute cerebral infarction (ACI). PubMed, SpringerLink, Wiley, EBSCO, Ovid, Web of Science, Wanfang, China National Knowledge Infrastructure, and VIP databases (last updated search in October 2014) were exhaustively searched, and data from the eligible studies were extracted and analyzed to assess the association between serum resistin levels and ACI. STATA software (version 12.0, Stata Corporation, College Station, TX, USA) was utilized for data analysis. Ten studies including 1829 ACI patients and 1557 healthy controls were eligible for inclusion in the meta-analysis. Our major result revealed that ACI patients exhibited higher serum resistin levels compared with healthy controls. Asubgroup analysis based on ethnicity showed a significant association between serum resistin levels and ACI in Asians, but surprisingly not in Caucasians. The results of our meta-analysis suggest that serum resistin levels are associated with an increased risk of ACI.
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页码:1919 / 1926
页数:7
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