MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells

被引:0
|
作者
Yuxia Li
Jie Zhang
Yajing Liu
Bingyue Zhang
Fubo Zhong
Shubin Wang
Zhengyu Fang
机构
[1] Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center,Biomedical Research Institute
[2] Peking University Shenzhen Hospital,Department of Medical Oncology
来源
BMC Cancer | / 18卷
关键词
Melanoma; Cisplatin; miR-30a-5p; IGF1R; Chemo-resistance;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Exosomal miR-140-5p inhibits osteogenesis by targeting IGF1R and regulating the mTOR pathway in ossification of the posterior longitudinal ligament
    Tang, Yifan
    Sun, Yanqing
    Zeng, Junkai
    Yuan, Bo
    Zhao, Yin
    Geng, Xiangwu
    Jia, Lianshun
    Zhou, Shengyuan
    Chen, Xiongsheng
    JOURNAL OF NANOBIOTECHNOLOGY, 2022, 20 (01)
  • [22] IGF REGULATES MIR-483-3P EXPRESSION IN THE DEVELOPING HUMAN PLACENTA VIA AN IGF1R/ERK PATHWAY
    Hibbert, Susan
    Farrokhnia, Farkhondeh
    Westwood, Melissa
    Aplin, John
    Forbes, Karen
    PLACENTA, 2011, 32 (09) : A140 - A140
  • [23] IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance
    Selfe, Joanna
    Goddard, Neil C.
    McIntyre, Alan
    Taylor, Kathryn R.
    Renshaw, Jane
    Popov, Sergey D.
    Thway, Khin
    Summersgill, Brenda
    Huddart, Robert A.
    Gilbert, Duncan C.
    Shipley, Janet M.
    JOURNAL OF PATHOLOGY, 2018, 244 (02): : 242 - 253
  • [24] Self activation of IGF1R signaling by cancer cells confers a paracrine metabolic advantage
    Lenz, Gal
    Hamilton, Angelica
    Huss, Janice
    Kane, Susan
    FASEB JOURNAL, 2016, 30
  • [25] Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells
    Lin, Ji-Fan
    Tsai, Te-Fu
    Lin, Yi-Chia
    Chen, Hung-En
    Chou, Kuang-Yu
    Hwang, Thomas I-Sheng
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2019, 54 (06) : 2106 - 2116
  • [26] MiR-30a-5p/CHD1 axis enhances cisplatin sensitivity of ovarian cancer cells via inactivating the Wnt/β-catenin pathway
    Wang, Xiaoyan
    Zhao, Hong
    Wang, Pei
    Zhang, Jinbin
    Li, Na
    Liu, Yangyang
    Zhang, Feng
    Yu, Yanling
    ANTI-CANCER DRUGS, 2022, 33 (10) : 989 - 998
  • [27] MiR-99a suppresses cell migration and invasion by regulating IGF1R in gastric cancer
    Xu, X-L
    Guo, A-X
    Pan, Q-Y
    Chang, A-L
    Zhao, C-R
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2019, 23 (17) : 7375 - 7382
  • [28] IGF1R activation and the in vitro antiproliferative efficacy of IGF1R inhibitor are inversely correlated with IGFBP5 expression in bladder cancer
    Neuzillet, Yann
    Chapeaublanc, Elodie
    Krucker, Clementine
    De Koning, Leanne
    Lebret, Thierry
    Radvanyi, Francois
    Bernard-Pierrot, Isabelle
    BMC CANCER, 2017, 17
  • [29] IGF1R activation and the in vitro antiproliferative efficacy of IGF1R inhibitor are inversely correlated with IGFBP5 expression in bladder cancer
    Yann Neuzillet
    Elodie Chapeaublanc
    Clémentine Krucker
    Leanne De Koning
    Thierry Lebret
    François Radvanyi
    Isabelle Bernard-Pierrot
    BMC Cancer, 17
  • [30] Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition
    Cedric Leroy
    Pedro Ramos
    Karen Cornille
    Debora Bonenfant
    Christine Fritsch
    Hans Voshol
    Mohamed Bentires-Alj
    Breast Cancer Research, 18