Comparing the effectiveness of metformin with lifestyle modification for the primary prevention of type II diabetes: a systematic review and meta-analysis

被引：0
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作者：
Sayedah Sarah Mousavi
Seyedeh Mahdieh Namayandeh
Hossein Fallahzadeh
Masoud Rahmanian
Mehdi Mollahosseini
机构：
[1] Shahid Sadoughi University of Medical Sciences and Health Services,Department of Biostatistics and Epidemiology, School of Public Health
[2] Shahid Sadoughi University of Medical Sciences and Health Services,Center for Healthcare Data Modeling, Departments of Biostatistics and Epidemiology, School of Public Health
[3] Shahid Sadoughi University of Medical Sciences and Health Services,Yazd Diabetes Research Center
[4] Shahid Sadoughi University of Medical Sciences and Health Services,Department of Community Nutrition, School of Public Health
来源：
BMC Endocrine Disorders | / 23卷
关键词：
Diabetes; Lifestyle modification; Metformin; Primary prevention; Systematic review; Meta-analysis;
D O I：
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学科分类号：
摘要：
This meta-analysis includes randomized clinical trials that directly evaluated two lifestyle modification and metformin treatment interventions. Our results indicate that long-term lifestyle modifications can prevent diabetes type II and decrease diabetes mellitus incidence down to one-quarter in comparison to metformin.
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