Effect of Oxidative Stress on the Junctional Proteins of Cultured Cerebral Endothelial Cells

被引:0
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作者
István A. Krizbai
Hannelore Bauer
Nicolaus Bresgen
Peter M. Eckl
Attila Farkas
Erzsébet Szatmári
Andreas Traweger
Katarzyna Wejksza
Hans-Christian Bauer
机构
[1] Institute of Biophysics,Biological Research Centre
[2] University of Salzburg,ABT, Department of Organismic Biology
[3] University of Salzburg,Department of Cell Biology
[4] Biological Research Centre,Institute of Biophysics
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关键词
cerebral endothelial cells; oxidative stress; occludin; tight junction; MAPK;
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摘要
1. There is increasing evidence that the cerebral endothelium and the blood–brain barrier (BBB) plays an important role in the oxidative stress-induced brain damage. The aim of the present study was to investigate the role of interendothelial junctional proteins in the BBB permeability increase induced by oxidative stress.
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页码:129 / 139
页数:10
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