Mechanisms of Disease: Helicobacter pylori-related gastric carcinogenesis—implications for chemoprevention

被引：0
作者：
Marco Romano
Vittorio Ricci
Raffaele Zarrilli
机构：
[1] Second University of Naples,Associate Professor of Gastroenterology at the Department of Internal Medicine–Gastroenterology Unit
[2] University of Pavia Medical School,Associate Professor of Physiology at the Department of Experimental Medicine
[3] Medical School of the University of Naples “Federico II”,Assistant Professor of Hygiene and Public Health at the Department of Preventive Medical Sciences
来源：
Nature Clinical Practice Gastroenterology & Hepatology | 2006年 / 3卷
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摘要：
This Review considers the bacterial virulence factors and host inflammatory responses involved in the development of gastric cancer afterHelicobacter pylori infection, as well as the signaling pathways affected and possible molecular targets for intervention. The effect of H. pylori eradication and the modification of environmental conditions on the progression of the gastric carcinogenic process triggered by H. pyloriare also discussed.
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页码：622 / 632
页数：10
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