Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

被引：0

作者：

Xu Chen

Yaqiao Li

Chao Wang

Yinyan Tang

Sue-Ann Mok

Richard M. Tsai

Julio C. Rojas

Anna Karydas

Bruce L. Miller

Adam L. Boxer

Jason E. Gestwicki

Michelle Arkin

Ana Maria Cuervo

Li Gan

机构：

[1] University of California,Gladstone Institute of Neurological Disease

[2] University of California,Department of Neurology

[3] University of California,Small Molecule Discovery Center, Department of Pharmaceutical Chemistry

[4] University of California,Institute for Neurodegenerative Disease, Department of Pharmaceutical Chemistry, Weill Institute for Neurosciences

[5] University of California,Memory and Aging Center

[6] Albert Einstein College of Medicine,Department of Developmental and Molecular Biology

[7] Institute for Aging Studies,undefined

[8] Albert Einstein College of Medicine,undefined

[9] Helen and Robert Appel Alzheimer’s Disease Research Institute,undefined

[10] Brain and Mind Research Institute,undefined

[11] Weill Cornell Medicine,undefined

来源：

Molecular Neurodegeneration | / 15卷

关键词：

Tauopathy; Tau secretion; Tau spreading; Autophagy-lysosomal pathway; p300/CBP;

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