Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

[1] Jucker M(2013)Self-propagation of pathogenic protein aggregates in neurodegenerative diseases Nature 501 45-51

[2] Walker LC(1991)Neuropathological stageing of Alzheimer-related changes Acta Neuropathol 82 239-259

[3] Braak H(2015)Spreading of pathology in neurodegenerative diseases: a focus on human studies Nat Rev Neurosci 16 109-120

[4] Braak E(2013)Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy J Neurosci 33 1024-1037

[5] Brettschneider J(2009)Transmission and spreading of tauopathy in transgenic mouse brain Nat Cell Biol 11 909-913

[6] Del Tredici K(2013)Tau degradation: the ubiquitin-proteasome system versus the autophagy-lysosome system Prog Neurobiol 105 49-59

[7] Lee VM(2010)Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau J Biol Chem 285 32539-32548

[8] Trojanowski JQ(2017)Extracellular low-n oligomers of tau cause selective synaptotoxicity without affecting cell viability Alzheimer's & Dementia 13 1270-1291

[9] Iba M(2016)Neuronal activity enhances tau propagation and tau pathology in vivo Nat Neurosci 19 1085-1092

[10] Clavaguera F(2017)The release and trans-synaptic transmission of tau via exosomes Mol Neurodegener 12 5-366

[1] Jucker M(2013)Self-propagation of pathogenic protein aggregates in neurodegenerative diseases Nature 501 45-51

[2] Walker LC(1991)Neuropathological stageing of Alzheimer-related changes Acta Neuropathol 82 239-259

[3] Braak H(2015)Spreading of pathology in neurodegenerative diseases: a focus on human studies Nat Rev Neurosci 16 109-120

[4] Braak E(2013)Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy J Neurosci 33 1024-1037

[5] Brettschneider J(2009)Transmission and spreading of tauopathy in transgenic mouse brain Nat Cell Biol 11 909-913

[6] Del Tredici K(2013)Tau degradation: the ubiquitin-proteasome system versus the autophagy-lysosome system Prog Neurobiol 105 49-59

[7] Lee VM(2010)Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau J Biol Chem 285 32539-32548

[8] Trojanowski JQ(2017)Extracellular low-n oligomers of tau cause selective synaptotoxicity without affecting cell viability Alzheimer's & Dementia 13 1270-1291

[9] Iba M(2016)Neuronal activity enhances tau propagation and tau pathology in vivo Nat Neurosci 19 1085-1092

[10] Clavaguera F(2017)The release and trans-synaptic transmission of tau via exosomes Mol Neurodegener 12 5-366