IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

被引:0
作者
Seth B. Coffelt
Kelly Kersten
Chris W. Doornebal
Jorieke Weiden
Kim Vrijland
Cheei-Sing Hau
Niels J. M. Verstegen
Metamia Ciampricotti
Lukas J. A. C. Hawinkels
Jos Jonkers
Karin E. de Visser
机构
[1] Netherlands Cancer Institute,Division of Immunology
[2] Leiden University Medical Center,Department of Molecular Cell Biology
[3] Centre for Biomedical Genetics,Division of Molecular Pathology
[4] Leiden University Medical Center,undefined
[5] Netherlands Cancer Institute,undefined
来源
Nature | 2015年 / 522卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Tumours maximize their chance of metastasizing by evoking a systemic inflammatory cascade in mouse models of spontaneous breast cancer metastasis.
引用
收藏
页码:345 / 348
页数:3
相关论文
共 55 条
[1]  
Quail DF(2013)Microenvironmental regulation of tumor progression and metastasis Nature Med. 19 1423-1437
[2]  
Joyce JA(2014)The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis Nature Cell Biol. 16 717-727
[3]  
McAllister SS(2013)Usefulness of pretreatment neutrophil to lymphocyte ratio in predicting disease-specific survival in breast cancer patients J. Breast Cancer 16 55-59
[4]  
Weinberg RA(2012)Usefulness of the neutrophil-to-lymphocyte ratio in predicting short- and long-term mortality in breast cancer patients Ann. Surg. Oncol. 19 217-224
[5]  
Noh H(2011)Tumor entrained neutrophils inhibit seeding in the premetastatic lung Cancer Cell 20 300-314
[6]  
Eomm M(2010)Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes Proc. Natl Acad. Sci. USA 107 21248-21255
[7]  
Han A(2014)Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma Nature 507 109-113
[8]  
Azab B(2006)Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis Cancer Cell 10 437-449
[9]  
Granot Z(2013)A preclinical mouse model of invasive lobular breast cancer metastasis Cancer Res. 73 353-363
[10]  
Kowanetz M(2005)VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche Nature 438 820-827