Powerful expression in Chinese Hamster Ovary cells using bacterial artificial chromosomes: parameters influencing productivity

被引:0
|
作者
Wolfgang Sommeregger
Andreas Gili
Thomas Sterovsky
Emilio Casanova
Renate Kunert
机构
[1] University of Natural Resources and Life Sciences,Vienna Institute of BioTechnology (VIBT), Department of Biotechnology
[2] Polymun Scientific Immunbiologische Forschung GmbH,undefined
[3] Ludwig Boltzmann Institute for Cancer Research (LBI-CR),undefined
关键词
Bacterial Artificial Chromosome; Recombinant Protein Production; Volumetric Titer; Spinner Flask; Viable Cell Density;
D O I
10.1186/1753-6561-7-S6-P25
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Expression of the porcine β2-adrenergic in Chinese hamster ovary cells
    Liang, W
    Bidwell, CA
    Collodi, PR
    Mills, SE
    JOURNAL OF ANIMAL SCIENCE, 2000, 78 (09) : 2329 - 2335
  • [22] MONITORING GENE-EXPRESSION IN CHINESE-HAMSTER OVARY CELLS USING SECRETED APOAEQUORIN
    INOUYE, S
    TSUJI, FI
    ANALYTICAL BIOCHEMISTRY, 1992, 201 (01) : 114 - 118
  • [23] Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells
    Martin Fussenegger
    Stefan Schlatter
    Daniel Dätwyler
    Xenia Mazur
    James E. Bailey
    Nature Biotechnology, 1998, 16 : 468 - 472
  • [24] Impact of hydrolysates on monoclonal antibody productivity, purification and quality in Chinese hamster ovary cells
    Ho, Steven C. L.
    Nian, Rui
    Woen, Susanto
    Chng, Jake
    Zhang, Peiqing
    Yang, Yuansheng
    JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2016, 122 (04) : 499 - 506
  • [25] Molecular Engineering of Exocytic Vesicle Traffic Enhances the Productivity of Chinese Hamster Ovary Cells
    Peng, Ren-Wang
    Fussenegger, Martin
    BIOTECHNOLOGY AND BIOENGINEERING, 2009, 102 (04) : 1170 - 1181
  • [26] RNA interference of cofilin in Chinese hamster ovary cells improves recombinant protein productivity
    Hammond, Stephanie
    Lee, Kelvin H.
    BIOTECHNOLOGY AND BIOENGINEERING, 2012, 109 (02) : 528 - 535
  • [27] Physiological responses of Chinese hamster ovary cells to a productivity-enhancing yeast extract
    Hu, Dongdong
    Zhao, Liang
    Wang, Jiaqi
    Fan, Li
    Liu, Xuping
    Wang, Haibin
    Tan, Wen-Song
    JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2018, 126 (05) : 636 - 643
  • [28] Profiling and engineering of microRNAs for enhancing recombinant protein productivity in Chinese hamster ovary cells
    Wan Ping Loh
    Bernard Loo
    Lihan Zhou
    Peiqing Zhang
    Dong Yup Lee
    Yuan Sheng Yang
    Kong Peng Lam
    BMC Proceedings, 7 (Suppl 6)
  • [29] Biphasic culture strategy for enhancing volumetric erythropoietin productivity of Chinese hamster ovary cells
    Yoon, Sung Kwan
    Kim, Sung Hyun
    Song, Ji Yong
    Lee, Gyun Min
    ENZYME AND MICROBIAL TECHNOLOGY, 2006, 39 (03) : 362 - 365
  • [30] Controlled proliferation by multigene metabolic engineering enhances the productivity of Chinese hamster ovary cells
    Fussenegger, M
    Schlatter, S
    Dätwyler, D
    Mazur, X
    Bailey, JE
    NATURE BIOTECHNOLOGY, 1998, 16 (05) : 468 - 472