Brilliant blue G, a P2X7 receptor antagonist, attenuates early phase of renal inflammation, interstitial fibrosis and is associated with renal cell proliferation in ureteral obstruction in rats

被引:0
作者
José Monteiro Sad Pereira
André Luis Barreira
Conrado Rodrigues Gomes
Felipe Mateus Ornellas
Débora Santos Ornellas
Luiz Carlos Miranda
Lucio Ronaldo Cardoso
Robson Coutinho-Silva
Alberto Schanaider
Marcelo M. Morales
Maurilo Leite
Christina Maeda Takiya
机构
[1] Universidade Federal do Rio de Janeiro,Programa de Pós
[2] Universidade Federal do Rio de Janeiro,Graduação em Ciências Cirúrgicas, Departamento de Cirurgia, Faculdade de Medicina
[3] Universidade Federal do Rio de Janeiro,Serviço de Urologia, Hospital Universitário Clementino Fraga Filho
[4] Universidade Federal do Rio de Janeiro,Serviço de Nefrologia, Hospital Universitário Clementino Fraga Filho
[5] Universidade Federal do Rio de Janeiro,Instituto de Biofísica Carlos Chagas Filho
来源
BMC Nephrology | / 21卷
关键词
Renal inflammation; P2X7 receptor; Unilateral ureteral obstruction; Macrophages;
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[21]  
Hirokawa G(2000)Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors Mol Pharm 58 82-1925
[22]  
Weng H(2014)P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica PLoS One 9 e110185-1456
[23]  
Hiura Y(2012)The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice Br J Pharmacol 165 183-233
[24]  
Takahashi R(2007)Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages J Immunol 179 1913-586
[25]  
Vonend O(2011)P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation Front Biosci (Schol Ed) 3 1443-41
[26]  
Turner CM(2012)Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infection PLoS One 7 e35812-119
[27]  
Chan CM(2012)Functional expression of the damage-associated molecular pattern receptor P2X7 on canine kidney epithelial cells Vet Immunol Immunopathol 150 228-594
[28]  
Loesch A(2010)Interactions of heat shock protein 47 with collagen and the stress response: an unconventional chaperone model? Life Sci 87 579-75
[29]  
Dell'Anna GC(2011)Heat shock protein 47: a novel biomarker of phenotypically altered collagen-producing cells Acta Histochem Cytochem 44 35-undefined
[30]  
Srai KS(1998)Up-regulation of HSP47 in the mouse kidneys with unilateral ureteral obstruction Kidney Int 54 110-undefined