Brilliant blue G, a P2X7 receptor antagonist, attenuates early phase of renal inflammation, interstitial fibrosis and is associated with renal cell proliferation in ureteral obstruction in rats

被引:0
作者
José Monteiro Sad Pereira
André Luis Barreira
Conrado Rodrigues Gomes
Felipe Mateus Ornellas
Débora Santos Ornellas
Luiz Carlos Miranda
Lucio Ronaldo Cardoso
Robson Coutinho-Silva
Alberto Schanaider
Marcelo M. Morales
Maurilo Leite
Christina Maeda Takiya
机构
[1] Universidade Federal do Rio de Janeiro,Programa de Pós
[2] Universidade Federal do Rio de Janeiro,Graduação em Ciências Cirúrgicas, Departamento de Cirurgia, Faculdade de Medicina
[3] Universidade Federal do Rio de Janeiro,Serviço de Urologia, Hospital Universitário Clementino Fraga Filho
[4] Universidade Federal do Rio de Janeiro,Serviço de Nefrologia, Hospital Universitário Clementino Fraga Filho
[5] Universidade Federal do Rio de Janeiro,Instituto de Biofísica Carlos Chagas Filho
来源
BMC Nephrology | / 21卷
关键词
Renal inflammation; P2X7 receptor; Unilateral ureteral obstruction; Macrophages;
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[1]  
Vénéreau E(2015)DAMPs from cell death to new life Front Immunol 6 422-S181
[2]  
Ceriotti C(2006)Purinergic signalling Br J Pharmacol 147 S172-117
[3]  
Bianchi ME(2003)The pattern of distribution of selected ATP-sensitive P2 receptor subtypes in normal rat kidney: an immunohistological study Cells Tissues Organs 175 105-e30
[4]  
Burnstock G(2005)The P2X7 ATP receptor in the kidney: a matter of life or death? Nephron Exp Nephrol 101 e24-1606
[5]  
Turner CM(2006)The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice Kidney Int 70 1599-179
[6]  
Vonend O(2012)P2X(7) receptor antagonism attenuates the hypertension and renal injury in Dahl salt sensitive rats Hypertens Res 35 173-166
[7]  
Chan C(2004)Glomerular expression of the ATP sensitive P2X7 receptor in diabetic and hypertensive rat models Kidney Int 66 157-1245
[8]  
Burnstock G(2004)Enhanced P2X7 activity in human fibroblasts from diabetic patients: a possible pathogenetic mechanism for vascular damage in diabetes Arterioscler Thromb Vasc Biol 24 1240-179
[9]  
Unwin RJ(2004)Altered ATPsensitive P2 receptor subtype expression in the Han:SPRD cy/+ rat, a model of autosomal dominant polycystic kidney disease Cells Tissues Organs 178 168-3185
[10]  
Hillman KA(2013)P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/Caspase 1 pathway Arthritis Rheum 65 3176-C788