A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes

被引:0
作者
Jin-Gu Lee
Yulong Fu
Jun-yi Zhu
Pei Wen
Joyce van de Leemput
Patricio E. Ray
Zhe Han
机构
[1] University of Maryland School of Medicine (UMSOM),Center for Precision Disease Modeling, Department of Medicine
[2] University of Maryland School of Medicine,Division of Endocrinology, Diabetes and Nutrition, Department of Medicine
[3] University of Virginia School of Medicine,Child Health Research Center, Department of Pediatrics
[4] University of Alabama Birmingham,Department of Pathology
来源
Cell & Bioscience | / 13卷
关键词
SNARE proteins; SNARE protective pool; APOL1; Renal toxicity; Nephrocytes; Serum resistance-associated (SRA) protein;
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[11]  
Katz A(2017)Apolipoprotein L1 gene effects on kidney transplantation Semin Nephrol 37 530-537
[12]  
Bernhardy AJ(2018)APOL1 genotype and renal function of black living donors J Am Soc Nephrol 29 1309-1316
[13]  
Tzur S(2014)APOL1 risk variants enhance podocyte necrosis through compromising lysosomal membrane permeability Am J Physiol Renal Physiol 307 F326-F336
[14]  
Rosset S(2015)Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells J Lipid Res 56 1583-1593
[15]  
Shemer R(2015)Protein domains of APOL1 and its risk variants Exp Mol Pathol 99 139-144
[16]  
Yudkovsky G(2015)Vascular smooth muscle cells contribute to APOL1-induced podocyte injury in HIV milieu Exp Mol Pathol 98 491-501
[17]  
Selig S(2015)Exon 4-encoded sequence is a major determinant of cytotoxicity of apolipoprotein L1 Am J Physiol Cell Physiol 309 C22-37
[18]  
Tarekegn A(2016)APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases Proc Natl Acad Sci U S A 113 830-837
[19]  
Vanhamme L(2016)APOL1-G0 or APOL1-G2 transgenic models develop preeclampsia but not kidney disease J Am Soc Nephrol 27 3600-3610
[20]  
Paturiaux-Hanocq F(2017)Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice Nat Med 23 429-438