Structural asymmetry of the basal nucleus of Meynert in men and women

被引：5
作者：
Amunts V.V. [1 ]
机构：
[1] Institute of the Brain, Russian Academy of Medical Sciences, Moscow
来源：
Neuroscience and Behavioral Physiology | 2007年 / 37卷 / 5期
关键词：
Meynert's nucleus; Morphometry; Neurohistology; Neurons; Total and satellite glial cells;
D O I：
10.1007/s11055-007-0045-0
中图分类号：
学科分类号：
摘要：
The structure of Meynert's nucleus was studied using quantitative neurohistological measures in 11 cases from the collection of the Institute of the Brain, Russian Academy of Medical Sciences. The set consisted of seven men and four women aged 19-60 years (apart from one aged 70 years) and were patients who had died suddenly with no history of neurological or mental diseases. The following parameters were measured: neuron field profile, neuron density, total and satellite glial density, and the proportion of glia consisting of satellite glia and the proportion of neurons surrounded by satellites. All individual measures were analyzed statistically and differences between the hemispheres were determined. On a background of a large spread in individual values, there was significant asymmetry in neuron field profile area in different directions in men and women and tendencies to a greater neuron density on the left and a greater glial cell density on the right. Measures of satellite glia showed particularly large variation, with the result that the only identifiable result was a greater proportion of satellite-surrounded neurons in the right hemisphere. Overall, there was a tendency to somewhat greater asymmetry in the structure of this nucleus in men. © Springer Science+Business Media, Inc. 2007.
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页码：517 / 521
页数：4
相关论文
共 18 条
  • [1] Avtandilov G.G., Medical Morphometry, (1990)
  • [2] Amunts V.V., Neuroglial relationships in the basal nucleus of Meynert in the brains of men and women in relation to asymmetry, Current Questions in Functional Interhemisphere Asymmetry, pp. 12-16, (2003)
  • [3] Amunts V.V., On the question of the asymmetry of the structural organization of the brain in men and women, Functional Interhemisphere Asymmetry. A Reader, pp. 214-218, (2004)
  • [4] Malofeeva L.I., Orzhekhovskaya N.S., Frontostriatal relationships in normal and pathological aging of the human brain, Arkhiv. Anat. Gistol. Émbriol. St. Petersburg, 97, 9, pp. 6-13, (1989)
  • [5] Markova E.G., Plasticity of Neurons in the Magnocellular Nuclei of the Basal Parts of the Human Brain in Normal, in Aging, and in Alzheimer's Disease, (2002)
  • [6] Orzhekhovskaya N.S., Sexual dimorphism. Structural differences in fields in the frontal areas in men and women, Luriya and Psychology in the 21st Century. Proceedings of the Second International Conference Celebrating the 100th Anniversary of the Birth of A. R. Luriya, pp. 104-105, (2002)
  • [7] Amunts K., Schlang G., Jancke J., Et al., Motor cortex and hand motor skills: Structural compliance in the human brain, Human Brain Mapping, 5, pp. 206-215, (1997)
  • [8] Arendt T., Bigl V., Jennsdedt A., Arendt A., Dendritic reorganisation in basal forebrain under degenerative conditions of the normal human basal forebrain, Neurosci., 14, pp. 1-14, (1985)
  • [9] Bear D., Schiff S., Saver J., Et al., Quantitative analysis of cerebral asymmetries. Fronto-occipital correlation, sexual dimorphism and association with handedness, Arch. Neurol., 43, pp. 598-608, (1986)
  • [10] Brockeandt A., Acetylcholine: A neurotransmitter for learning and memory?, Brain Res. Rev., 21, pp. 285-300, (1996)
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