Technology Insight: imaging neurodegeneration in Parkinson's disease

被引：0
|
作者：
David J Brooks
机构：
[1] DJ Brooks is Hartnett Professor of Neurology in the Faculty of Medicine at Imperial College,
[2] and Head of the Neurology Group at the Medical Research Council Clinical Sciences Centre at Hammersmith Hospital,undefined
[3] London,undefined
[4] and Head of Neurology,undefined
[5] Medical Diagnostics,undefined
[6] GE Healthcare,undefined
[7] Amersham,undefined
[8] UK.,undefined
来源：
Nature Clinical Practice Neurology | 2008年 / 4卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Currently, idiopathic Parkinson's disease can only be diagnosed definitively by the demonstration of intracellular Lewy body inclusions on histological specimens of brain tissue—an approach that is impractical in living individuals. In this Review, David Brooks discusses recent advances in noninvasive imaging approaches that are providing important insights into the structural, pathophysiological and pharmacological changes associated with Parkinson's disease, and could have major implications for the future diagnosis and management of this condition.
引用
收藏
页码：267 / 277
页数：10
相关论文
共 50 条
  • [41] Cerebrospinal fluid markers of neurodegeneration in Parkinson's disease
    Vranova, H.
    Nevrly, M.
    Mares, J.
    Kanovsky, P.
    Stejskal, D.
    MOVEMENT DISORDERS, 2009, 24 : S285 - S286
  • [42] Sleep and Neurodegeneration in a Mouse Model of Parkinson's Disease
    Martin, T. Gallego
    Chuan, B.
    Callio, J.
    Guo, L.
    Obidike, N.
    Shah, F.
    Bueno, M.
    Chu, C. T.
    Mora, A. L.
    O'Donnell, C. P.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
  • [43] Angiogenin and tRNA fragments in Parkinson's disease and neurodegeneration
    Prehn, Jochen H. M.
    Jirstrom, Elisabeth
    ACTA PHARMACOLOGICA SINICA, 2020, 41 (04): : 442 - 446
  • [44] Lewy pathology and neurodegeneration in premotor Parkinson's disease
    Del Tredici, Kelly
    Braak, Heiko
    MOVEMENT DISORDERS, 2012, 27 (05) : 597 - 607
  • [45] Methylation status in Parkinson's disease and neurodegeneration processes
    Obeid, R.
    Dillmann, U.
    Schadt, A.
    Fassbender, K.
    Herrmann, W.
    JOURNAL OF NEURAL TRANSMISSION, 2009, 116 (02) : 244 - 244
  • [46] ER stress and Parkinson's disease: relevance to neurodegeneration
    Hasegawa, Takafumi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2014, 124 : 40P - 40P
  • [47] Speech difficulties and dopaminergic neurodegeneration in Parkinson's Disease
    Polychronis, S.
    Ribba, B.
    Nasios, G.
    Dardiotis, E.
    Pagano, G.
    MOVEMENT DISORDERS, 2023, 38 : S566 - S566
  • [48] Natural Products Combating Neurodegeneration: Parkinson's Disease
    Solayman, Md.
    Islam, Md. Asiful
    Alam, Fahmida
    Khalil, Md. Ibrahim
    Kamal, Mohammad Amjad
    Gan, Siew Hua
    CURRENT DRUG METABOLISM, 2017, 18 (01) : 50 - 61
  • [49] Tetracycline repurposing in neurodegeneration: focus on Parkinson’s disease
    Mariza Bortolanza
    Glauce C. Nascimento
    Sergio B. Socias
    Diego Ploper
    Rosana N. Chehín
    Rita Raisman-Vozari
    Elaine Del-Bel
    Journal of Neural Transmission, 2018, 125 : 1403 - 1415
  • [50] Tetracycline repurposing in neurodegeneration: focus on Parkinson's disease
    Bortolanza, Mariza
    Nascimento, Glauce C.
    Socias, Sergio B.
    Ploper, Diego
    Chehin, Rosana N.
    Raisman-Vozari, Rita
    Del-Bel, Elaine
    JOURNAL OF NEURAL TRANSMISSION, 2018, 125 (10) : 1403 - 1415
12345