Technology Insight: imaging neurodegeneration in Parkinson's disease

被引：0
|
作者：
David J Brooks
机构：
[1] DJ Brooks is Hartnett Professor of Neurology in the Faculty of Medicine at Imperial College,
[2] and Head of the Neurology Group at the Medical Research Council Clinical Sciences Centre at Hammersmith Hospital,undefined
[3] London,undefined
[4] and Head of Neurology,undefined
[5] Medical Diagnostics,undefined
[6] GE Healthcare,undefined
[7] Amersham,undefined
[8] UK.,undefined
来源：
Nature Clinical Practice Neurology | 2008年 / 4卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Currently, idiopathic Parkinson's disease can only be diagnosed definitively by the demonstration of intracellular Lewy body inclusions on histological specimens of brain tissue—an approach that is impractical in living individuals. In this Review, David Brooks discusses recent advances in noninvasive imaging approaches that are providing important insights into the structural, pathophysiological and pharmacological changes associated with Parkinson's disease, and could have major implications for the future diagnosis and management of this condition.
引用
收藏
页码：267 / 277
页数：10
相关论文
共 50 条
  • [31] Calpain Mediated Neurodegeneration in Parkinson’s disease
    V. H. Knaryan
    Neurochemical Journal, 2023, 17 : 632 - 638
  • [32] CSF markers of neurodegeneration in Parkinson’s disease
    Hana Přikrylová Vranová
    Jan Mareš
    Martin Nevrlý
    David Stejskal
    Jana Zapletalová
    Petr Hluštík
    Petr Kaňovský
    Journal of Neural Transmission, 2010, 117 : 1177 - 1181
  • [33] PET assessment of neurodegeneration in Parkinson's disease
    de la Fuente-Fernandez, R.
    PARKINSONISM & RELATED DISORDERS, 2009, 15 : S27 - S27
  • [34] Imaging of iron and transcranial sonography in Parkinson's disease: complementary imaging modalities to map nigral neurodegeneration?
    Prasuhn, Jannik
    Strautz, Robert
    Lemmer, Felicitas
    Dreischmeier, Shalida
    Berg, Daniela
    Klein, Christine
    Kasten, Meike
    Heldmann, Marcus
    Bruggemann, Norbert
    JOURNAL OF NEURAL TRANSMISSION, 2019, 126 (05) : 685 - 685
  • [35] Shared Mechanisms of Neurodegeneration in Alzheimer's Disease and Parkinson's Disease
    Xie, Anmu
    Gao, Jing
    Xu, Lin
    Meng, Dongmei
    BIOMED RESEARCH INTERNATIONAL, 2014, 2014
  • [36] Imaging in Parkinson disease - a window to neurodegeneration, a tool to assess neuroprotection?
    Marek, K
    ARCHIVES OF NEUROLOGY, 2000, 57 (08) : 1237 - 1237
  • [37] Diffusion tensor and restriction spectrum imaging reflect different aspects of neurodegeneration in Parkinson's disease
    Hope, Tuva R.
    Selnes, Per
    Rektorova, Irena
    Anderkova, Lubomira
    Nemcova-Elfmarkova, Nela
    Balazova, Zuzana
    Dale, Anders
    Bjornerud, Atle
    Fladby, Tormod
    PLOS ONE, 2019, 14 (05):
  • [38] COX-2 and neurodegeneration in Parkinson's disease
    Teismann, P
    Vila, M
    Choi, DK
    Tieu, K
    Wu, DC
    Jackson-Lewis, V
    Przedborski, S
    PARKINSON'S DISEASE: THE LIFE CYCLE OF THE DOPAMINE NEURON, 2003, 991 : 272 - 277
  • [39] Angiogenin and tRNA fragments in Parkinson’s disease and neurodegeneration
    Jochen H M Prehn
    Elisabeth Jirström
    Acta Pharmacologica Sinica, 2020, 41 : 442 - 446
  • [40] Neurodegeneration in Parkinson's Disease: Genetics Enlightens Physiopathology
    Corti, Olga
    Fournier, Margot
    Brice, Alexis
    JOURNAL OF NEURAL TRANSMISSION-SUPPLEMENT, 2009, (73): : 215 - 221
12345