Technology Insight: imaging neurodegeneration in Parkinson's disease

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作者
David J Brooks
机构
[1] DJ Brooks is Hartnett Professor of Neurology in the Faculty of Medicine at Imperial College,
[2] and Head of the Neurology Group at the Medical Research Council Clinical Sciences Centre at Hammersmith Hospital,undefined
[3] London,undefined
[4] and Head of Neurology,undefined
[5] Medical Diagnostics,undefined
[6] GE Healthcare,undefined
[7] Amersham,undefined
[8] UK.,undefined
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摘要
Currently, idiopathic Parkinson's disease can only be diagnosed definitively by the demonstration of intracellular Lewy body inclusions on histological specimens of brain tissue—an approach that is impractical in living individuals. In this Review, David Brooks discusses recent advances in noninvasive imaging approaches that are providing important insights into the structural, pathophysiological and pharmacological changes associated with Parkinson's disease, and could have major implications for the future diagnosis and management of this condition.
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页码:267 / 277
页数:10
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