Downregulation of long noncoding RNA MEG3 is associated with poor prognosis and promoter hypermethylation in cervical cancer

被引:0
作者
Jun Zhang
Zhongqiu Lin
Yali Gao
Tingting Yao
机构
[1] Jinan University,Department of Obstetrics and Gynecology, The Second Clinical Medical College (Shenzhen People’s Hospital)
[2] Sun Yat-sen University,Department of Gynecological Oncology, Sun Yat
[3] Jinan University,sen Memorial Hospital
来源
Journal of Experimental & Clinical Cancer Research | / 36卷
关键词
Cervical cancer; Diagnosis; Long noncoding RNA; Methylation; Prognosis;
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[1]  
Siegel R(2012)Cancer statistics CA Cancer J Clin 62 10-29
[2]  
Naishadham D(2009)Evolution and functions of long noncoding RNAs Cell 136 629-641
[3]  
Jemal A(2011)Human cancer long non-coding RNA transcriptomes PLoS One 6 e25915-6400
[4]  
Ponting CP(2012)Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs Nucleic Acids Res 40 6391-1073
[5]  
Oliver PL(2014)Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer Tumor Biol 35 1065-9
[6]  
Reik W(2015)Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression J Exp Clin Cancer Res 34 79-9
[7]  
Gibb EA(2015)Decreased expression of long noncoding RNA MEG3 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer Tumour Biol 36 4851-85
[8]  
Vucic EA(2016)Decreased expression of MEG3 contributes to retinoblastoma progression and affects retinoblastoma cell growth by regulating the activity of Wnt/β-catenin pathway Tumour Biol 37 1461-13
[9]  
Enfield KS(2011)Promoter hypermethylation influences the suppressive role of maternally expressed 3, a long non-coding RNA, in the development of epithelial ovarian cancer Oncol Rep 32 277-398
[10]  
Stewart GL(2016)Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21 Cancer Biol Ther 17 104-266