Establishment of patient-derived gastric cancer xenografts: a useful tool for preclinical evaluation of targeted therapies involving alterations in HER-2, MET and FGFR2 signaling pathways

被引:0
作者
Haiyong Wang
Jun Lu
Jian Tang
Shitu Chen
Kuifeng He
Xiaoxia Jiang
Weiqin Jiang
Lisong Teng
机构
[1] The First Affiliated Hospital,Department of surgical oncology
[2] College of Medicine,Department of oncology
[3] Zhejiang University,undefined
[4] Jiaxing First Hospital,undefined
来源
BMC Cancer | / 17卷
关键词
Gastric cancer; Xenograft; cMet; Her2; FGFR; Targeted therapy;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 168 条
[1]  
Jemal A(2007)Global cancer statistics CA Cancer J Clin 57 43-66
[2]  
Siegel R(2011)Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world CA Cancer J Clin 61 69-90
[3]  
Ward E(2006)Cetuximab for the Treatment of Colorectal Cancer J Clin Oncol 24 2137-2150
[4]  
Murray T(2007)Novel therapeutic targets in non-small cell lung cancer N Engl J Med 357 2040-2048
[5]  
Xu J(2013)Targeted Therapy for Gastric Cancer Curr Opin Pharmacol 13 394-401
[6]  
Thun MJ(2012)Trastuzumab in breast cancer Curr Treat Options Oncol 13 377-389
[7]  
Jemal A(2006)Patient-derived tumour xenografts as models for oncology drug development N Engl J Med 354 640-644
[8]  
Bray F(2012)A new model of patient tumor-derived breast cancer xenografts for preclinical assays Nat Rev Clin Oncol 9 338-350
[9]  
Center MM(2007)Patient-derived tumor xenografts: transforming clinical samples into mouse models Clin Cancer Res 13 3989-3998
[10]  
Ferlay J(2013)Establishment of patient-derived non-small cell lung cancer xenograft models with genetic aberrations within EGFR, KRAS and FGFR1: useful tools for preclinical studies of targeted therapies Cancer Res 73 5315-5319