Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway

被引:0
作者
Dongdong Wu
Zhengguo Liu
Jianmei Li
Qianqian Zhang
Peiyu Zhong
Tieshan Teng
Mingliang Chen
Zhongwen Xie
Ailing Ji
Yanzhang Li
机构
[1] Henan University College of Medicine,School of Basic Medical Sciences
[2] Anhui Agricultural University,State Key Laboratory of Tea Plant Biology and Utilization
[3] Henan University,Henan International Joint Laboratory for Nuclear Protein Regulation
来源
Cancer Cell International | / 19卷
关键词
EGCG; Thyroid carcinoma; Apoptosis; Angiogenesis; Signaling pathway;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 177 条
[21]  
Capdevila J(2017)Emerging importance of dietary phytochemicals in fight against cancer: role in targeting cancer stem cells Crit Rev Food Sci Nutr 57 3449-3319
[22]  
Mayor R(2006)Specific killing of multiple myeloma cells by (–)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications Blood 108 2804-3958
[23]  
Mancuso FM(2003)Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals Clin Cancer Res 9 3312-2387
[24]  
Brose MS(2017)Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-κB signaling pathways Sci Rep 7 455-3095
[25]  
Nutting CM(2017)Hydrogen sulfide acts as a double-edged sword in human hepatocellular carcinoma cells through EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways Sci Rep 7 5134-115
[26]  
Jarzab B(2018)PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways BMC Cancer 18 499-24
[27]  
Broecker-Preuss M(2014)CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers Cancer Res 74 3947-150
[28]  
Müller S(2008)Ki-67 predicts outcome in advanced-stage mantle cell lymphoma patients treated with anti-CD20 immunochemotherapy: results from randomized trials of the European MCL network and the German low grade lymphoma study group Blood 111 2385-15
[29]  
Britten M(2000)Vascular endothelial growth factor/KDR activated microvessel density versus CD31 standard microvessel density in non-small cell lung cancer Cancer Res 60 3088-987
[30]  
Wang J(2017)Cell cycle proteins as promising targets in cancer therapy Nat Rev Cancer 17 93-441