Perineural invasion is a better prognostic factor than extranodal extension in head and neck cancer

[1] Marur S(2016)Head and neck squamous cell carcinoma: update on epidemiology, diagnosis, and treatment Mayo Clin Proc 91 386-396

[2] Forastiere AA(2019)High-risk pathological features at the time of salvage surgery predict poor survival after definitive therapy in patients with head and neck squamous cell carcinoma Oral Oncol 88 9-15

[3] Haque S(2017)Prognostic significance of surgical extranodal extension in head and neck squamous cell carcinoma patients Jpn J Clin Oncol 47 699-704

[4] Karivedu V(2017)Assessment of adjuvant therapy in resected head and neck cancer with high-risk features Oral Oncol 74 15-20

[5] Riaz MK(2004)Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer N Engl J Med 350 1945-1952

[6] Matsumoto F(2004)Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck N Engl J Med 350 1937-1944

[7] Mori T(1985)Nerves and neurotropic carcinomas Ann Otol Rhinol Laryngol 94 426-427

[8] Matsumura S(2009)Perineural invasion in cancer: a review of the literature Cancer. 115 3379-3391

[9] Ajmani GS(2016)Adjuvant radiotherapy for early head and neck squamous cell carcinoma with perineural invasion: a systematic review Head Neck 38 E2350-E2357

[10] Nocon CC(1999)Lymph node metastasis in head and neck squamous cells carcinoma: multivariate analysis of prognostic variables J Exp Clin Cancer Res 18 79-83

[1] Marur S(2016)Head and neck squamous cell carcinoma: update on epidemiology, diagnosis, and treatment Mayo Clin Proc 91 386-396

[2] Forastiere AA(2019)High-risk pathological features at the time of salvage surgery predict poor survival after definitive therapy in patients with head and neck squamous cell carcinoma Oral Oncol 88 9-15

[3] Haque S(2017)Prognostic significance of surgical extranodal extension in head and neck squamous cell carcinoma patients Jpn J Clin Oncol 47 699-704

[4] Karivedu V(2017)Assessment of adjuvant therapy in resected head and neck cancer with high-risk features Oral Oncol 74 15-20

[5] Riaz MK(2004)Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer N Engl J Med 350 1945-1952

[6] Matsumoto F(2004)Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck N Engl J Med 350 1937-1944

[7] Mori T(1985)Nerves and neurotropic carcinomas Ann Otol Rhinol Laryngol 94 426-427

[8] Matsumura S(2009)Perineural invasion in cancer: a review of the literature Cancer. 115 3379-3391

[9] Ajmani GS(2016)Adjuvant radiotherapy for early head and neck squamous cell carcinoma with perineural invasion: a systematic review Head Neck 38 E2350-E2357

[10] Nocon CC(1999)Lymph node metastasis in head and neck squamous cells carcinoma: multivariate analysis of prognostic variables J Exp Clin Cancer Res 18 79-83