IRE1 gives weight to obesity-associated inflammation

被引：0
作者：
Bojan Bujisic
Fabio Martinon
机构：
[1] University of Lausanne,Bojan Bujisic and Fabio Martinon are in the Department of Biochemistry
[2] Epalinges,undefined
[3] Switzerland.,undefined
来源：
Nature Immunology | 2017年 / 18卷
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学科分类号：
摘要：
IRE1α is a stress sensor that is activated by a high-fat diet. In adipose-tissue macrophages, it serves as a major switch toward pro-inflammatory M1 polarization and thereby contributes to obesity and associated diseases.
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页码：479 / 480
页数：1
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