Unexpected pulmonary tumor: Metastasis from a benign uterine leiomyoma in a post-menopausal woman: A case report

被引：13

作者：

Efared B. ^{[1
]}

Atsame-Ebang G. ^{[1
]}

Sani R. ^{[2
]}

Tahiri L. ^{[1
]}

Sidibe I.S. ^{[1
]}

Erregad F. ^{[1
]}

Hammas N. ^{[1
,3
,4
]}

Smahi M. ^{[2
,4
]}

Serraj M. ^{[4
,5
]}

Chbani L. ^{[1
,3
,4
]}

Fatemi H.E. ^{[1
,3
,4
]}

机构：

[1] Department of Pathology, Hassan II University Hospital, Fès

[2] Department of Thoracic Surgery, Hassan II University Hospital, Fès

[3] Laboratory of Translational and Biomedical Research, Faculty of Medicine and Pharmacology, Sidi Mohamed Ben Abdellah University, Fès

[4] Faculty of Medicine and Pharmacology, Sidi Mohamed Ben Abdellah University, Fès

[5] Department of Pneumology, Hassan II University Hospital, Fès

来源：

BMC Research Notes | / 10卷 / 1期

关键词：

Benign; Leiomyoma; Lung; Metastasis; Uterus;

D O I：

10.1186/s13104-017-2998-6

中图分类号：

学科分类号：

摘要：

Background: The occurrence of lung metastasis from benign uterine leiomyomas is rarely reported especially in post menopausal women. The pathogenesis of these metastatic benign tumors still remains a subject of various speculations. Case presentation: A 57-year-old woman presented with a chronic cough and dyspnea. She had undergone 8 years previously, hysterectomy for benign leiomyomas. A chest computed tomography scan showed a 4 cm solitary nodular parenchymal tumor that increased in size after 12 months. The histological analysis of the biopsy from this nodule showed a benign tumor with regular spindle cells disposed in intersected fascicles. At immunohistochemical analysis, the tumor cells were positive for smooth muscle markers and oestrogen-progesterone receptors with a low mitotic index assessed by Ki-67. These features were consistent with a benign metastasizing uterine leiomyoma. At the multidisciplinary meeting, prescription of an aromatase inhibitor has been decided for the patient. Conclusions: Benign metastasizing uterine leiomyomas of the lung are very rare tumors. Although extremely rare in post menopausal women, their diagnosis should be considered in symptomatic patients with a history of hysterectomy for leiomyomas. © 2017 The Author(s).

引用

共 15 条

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