Longitudinal Effects of Syndemics on ART Non-adherence Among Sexual Minority Men

被引：0
作者：
Audrey Harkness
Sierra A. Bainter
Conall O’Cleirigh
Noelle A. Mendez
Kenneth H. Mayer
Steven A. Safren
机构：
[1] University of Miami,Department of Psychology
[2] The Fenway Institute,Fenway Community Health
[3] Harvard Medical School/Massachusetts General Hospital,Department of Psychiatry
[4] Harvard Medical School/Beth Israel Deaconess Medical Center,Division of Infectious Disease, Department of Medicine
来源：
AIDS and Behavior | 2018年 / 22卷
关键词：
HIV; Sexual minority; Syndemics; Antiretroviral therapy/ART; Adherence;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This study examined longitudinally the additive effect of syndemics, or co-occurring psychosocial problems, on antiretroviral treatment (ART) non-adherence among 390 HIV-positive sexual minority men. Participants completed measures of ART adherence (reduced to a non-adherence score using exploratory factor analysis) and six syndemic conditions. We employed multilevel modeling with the number of syndemics as a longitudinal predictor of non-adherence, and logistic regression with baseline syndemics predicting follow up viral load. Number of syndemics was a significant longitudinal predictor of non-adherence, with each additional syndemic associated with a 0.13 increase in non-adherence (p = 0.004). Each additional syndemic was also associated with 1.27 greater odds of detectable viral load (p = 0.002). Among HIV-positive sexual minority men in this sample, more syndemics were associated with lower ART adherence and greater odds of detectable viral load, suggesting the need for behavioral intervention to facilitate care for this population.
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页码：2564 / 2574
页数：10
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