Improving Dry Powder Inhaler Performance by Surface Roughening of Lactose Carrier Particles

[1] Hersey JA(1975)Ordered mixing: a new concept in powder mixing practice Powder Technol 11 41-4

[2] Donovan MJ(2010)Influence of size and surface roughness of large lactose carrier particles in dry powder inhaler formulations Int J Pharm 402 1-9

[3] Smyth HDC(1998)Effect of surface morphology of carrier lactose on dry powder inhalation property of pranlukast hydrate Int J Pharm 172 179-88

[4] Kawashima Y(2002)Characterization of a surface modified dry powder inhalation carrier prepared by “particle smoothing” J Pharm Pharmacol 54 1339-44

[5] Serigano T(2008)What is the role of particle morphology in pharmaceutical powder aerosols? Expert Opin Drug Deliv 5 909-14

[6] Hino T(2013)Effects of mechanical impaction on aerosol performance of particles with different surface roughness Powder Technol 236 164-70

[7] Yamamoto H(2011)The impact of spray drying outlet temperature on the particle morphology of mannitol Powder Technol 213 27-35

[8] Takeuchi H(2000)Crystallization of lactose from carbopol gels Pharm Res 17 879-86

[9] Young PM(2000)The influence of crystallization conditions on the morphology of lactose intended for use as a carrier for dry powder aerosols J Pharm Pharmacol 52 633-43

[10] Cocconi D(2009)Effective modification of particle surface properties using ultrasonic water mist AAPS PharmSciTech 10 282-8

[1] Hersey JA(1975)Ordered mixing: a new concept in powder mixing practice Powder Technol 11 41-4

[2] Donovan MJ(2010)Influence of size and surface roughness of large lactose carrier particles in dry powder inhaler formulations Int J Pharm 402 1-9

[3] Smyth HDC(1998)Effect of surface morphology of carrier lactose on dry powder inhalation property of pranlukast hydrate Int J Pharm 172 179-88

[4] Kawashima Y(2002)Characterization of a surface modified dry powder inhalation carrier prepared by “particle smoothing” J Pharm Pharmacol 54 1339-44

[5] Serigano T(2008)What is the role of particle morphology in pharmaceutical powder aerosols? Expert Opin Drug Deliv 5 909-14

[6] Hino T(2013)Effects of mechanical impaction on aerosol performance of particles with different surface roughness Powder Technol 236 164-70

[7] Yamamoto H(2011)The impact of spray drying outlet temperature on the particle morphology of mannitol Powder Technol 213 27-35

[8] Takeuchi H(2000)Crystallization of lactose from carbopol gels Pharm Res 17 879-86

[9] Young PM(2000)The influence of crystallization conditions on the morphology of lactose intended for use as a carrier for dry powder aerosols J Pharm Pharmacol 52 633-43

[10] Cocconi D(2009)Effective modification of particle surface properties using ultrasonic water mist AAPS PharmSciTech 10 282-8